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LACONORTE study: Efficacy and security of lacosamide as first add-on therapy for focal-onset epilepsy in real-life setting.

Author: Abella-CorralJavier, Bellas LamasPaula, Castro VilanovaMaría Dolores, GareaMaría José, Gil LópezJuan Antonio, López-GonzálezFrancisco Javier, Muñoz-LopetegiAmaia, Pato PatoAntonio, PozaJuan José, Rodríguez-OsorioXiana, Ruiz-MartínezJavier

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Lacosamide is efficacious and safe when used as first add-on therapy for focal-onset epilepsy. Most adverse events were mild and/or transient.
Paper Details　
Original Abstract of the Article :
RATIONALE: Many patients with epilepsy need a second antiepileptic drug (AED), due either to inefficacy or side effects of the first tried one. We evaluated the efficacy and safety of lacosamide (LCM) as first add-on therapy in the real-life setting. METHODS: LACONORTE is a multicenter, retrospecti...See full text at original site
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引用元：
https://doi.org/10.1016/j.eplepsyres.2018.05.011

データ提供：米国国立医学図書館（NLM）

Lacosamide: A Promising Add-on Therapy for Focal-Onset Epilepsy

Epilepsy, a neurological condition characterized by seizures, can significantly disrupt a person’s life. This study investigates the effectiveness of lacosamide (LCM) as an add-on therapy for focal-onset epilepsy. Researchers conducted a retrospective study to evaluate the efficacy and safety of LCM in a real-life setting. The study found that LCM effectively reduced seizure frequency and was generally well-tolerated, suggesting its potential as a valuable therapeutic option for patients with focal-onset epilepsy.

Lacosamide: A Beacon of Hope for Patients with Focal-Onset Epilepsy

This research highlights the potential of lacosamide as a promising add-on therapy for focal-onset epilepsy. LCM, like a calm oasis in a desert of seizures, can help reduce seizure frequency and improve quality of life for patients with this challenging condition. The study provides encouraging evidence for the effectiveness and safety of LCM in real-life clinical practice.

Optimizing Epilepsy Treatment: Personalized Strategies

The study emphasizes the importance of personalized treatment strategies for epilepsy, acknowledging the unique needs and responses of each patient. It’s like finding the most suitable path through a complex desert landscape. The findings underscore the need for careful consideration of individual patient characteristics, including seizure type and medication tolerance, in selecting the most appropriate epilepsy treatment.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of lacosamide as an add-on therapy for focal-onset epilepsy. It’s like discovering a hidden spring in the desert, offering a source of relief for patients with this challenging condition. The findings are encouraging for the future of epilepsy treatment, highlighting the potential for improving patient outcomes with personalized approaches.

Date :
  1. Date Completed 2019-04-05
  2. Date Revised 2019-04-05
Further Info :

Pubmed ID

29890341

DOI: Digital Object Identifier

10.1016/j.eplepsyres.2018.05.011

Related Literature

Article Analysis
・Side Effects of lacosamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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