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Three months of rifapentine and isoniazid for latent tuberculosis infection in hemodialysis patients: High rates of adverse events.
Author: ChenTun-Chieh, ChenYen-Hsu, ChiuYi-Wen, HsiehMin-Han, HwangShang-Jyh, LinShang-Yi, LuPo-Liang
Original Abstract of the Article :
The consequences of once-weekly rifapentine plus isoniazid for 3 months (3HP) against latent tuberculosis infections in hemodialysis patients have not been studied before. This is the first study to evaluate the safety and tolerability of 3HP in this population and revealed a completion rate of 65.4...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jmii.2018.05.003
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of Tuberculosis Treatment
Tuberculosis (TB) is a serious infectious disease that can have devastating consequences, like a persistent desert drought that can drain vital resources. This study investigates the safety and tolerability of a 3-month regimen of rifapentine and isoniazid for latent TB infection in hemodialysis patients. The researchers explore the potential for this regimen to effectively treat latent TB while minimizing side effects.
A Challenging Journey Through the Desert of TB Treatment
The study found that while the 3-month regimen was not associated with hepatotoxicity, it did have a high rate of adverse events. This finding highlights the need for careful monitoring and individualized approaches to TB treatment in hemodialysis patients. The researchers, like explorers navigating a challenging terrain, are seeking safe and effective ways to combat TB in this vulnerable population.
Finding Safe Passage Through the Desert of TB
This research provides valuable insights into the challenges of treating latent TB in hemodialysis patients. The study highlights the need for further research to optimize treatment regimens and minimize side effects. It is crucial to work closely with your healthcare provider to discuss the most appropriate treatment plan for your individual needs.
Dr.Camel's Conclusion
This study underscores the need for continued research to develop safer and more effective treatment regimens for latent TB in hemodialysis patients. Like a desert traveler seeking the best route to an oasis, researchers are tirelessly working to find solutions that improve outcomes for patients facing this challenging disease.
Date :
- Date Completed 2019-09-12
- Date Revised 2019-09-12
Further Info :
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