Paper Details 
Original Abstract of the Article :
Persistent psychotic symptoms will develop in up to 60% of patients with Parkinson disease (PD). The initial approach to the management of PD psychosis (PDP) begins with addressing concurrent systemic conditions associated with psychotic behavior, such as delirium, medical conditions (eg, infections...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007727/

データ提供:米国国立医学図書館(NLM)

Treating Psychotic Symptoms in Parkinson's Disease

This research delves into the critical realm of managing psychotic symptoms in Parkinson's disease (PD). It's like navigating a vast desert, where every step is crucial to ensure a stable journey. This study employed a systematic approach, analyzing the most effective methods for addressing these challenging symptoms.

A Multifaceted Approach to Managing PD Psychosis

The findings highlight the importance of a comprehensive strategy, starting with addressing any underlying medical or psychiatric conditions that might contribute to the psychosis. It's like clearing the sand dunes and ensuring a clear path before embarking on the real journey. This involves a thorough review of medications and, if possible, reducing or eliminating those that might trigger psychotic symptoms. The goal is to strike a delicate balance – improving drug-related psychotic symptoms while not significantly worsening the motor symptoms of PD, much like carefully navigating a tricky desert terrain.

Second-Generation Antipsychotics: A Potential Oasis

When additional measures are needed for chronic PDP treatment, the study recommends exploring second-generation antipsychotics, such as clozapine, pimavanserin, or quetiapine. These drugs offer a potential oasis in the desert of PD psychosis, providing relief without the significant side effects of their first-generation counterparts. In patients with comorbid dementia, the addition of a cholinesterase inhibitor might also be beneficial.

Dr.Camel's Conclusion

This research provides valuable insights into the complex management of PD psychosis. It emphasizes a multi-pronged approach, focusing on identifying and addressing underlying factors, carefully adjusting medications, and exploring the potential benefits of second-generation antipsychotics. Remember, managing PD psychosis is a journey through a challenging landscape, and this study equips us with the necessary tools to navigate it effectively.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

29955532

DOI: Digital Object Identifier

PMC6007727

Related Literature

SNS
PICO Info
in preparation
Languages

English

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