A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia.

Author: ChalermrojN, KhunkhetS, SrisuwanwattanaP, SuchonwanitP

Paper Details 
Original Abstract of the Article :
BACKGROUND: The synergism of combined use between oral finasteride and topical minoxidil has been established in treating androgenetic alopecia among men. However, the concern regarding adverse effects of finasteride use has been rising. OBJECTIVE: To compare the efficacy and safety of topical solu...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/jdv.15171

データ提供:米国国立医学図書館(NLM)

A Winning Combination for Hair Loss: Topical Finasteride and Minoxidil

The quest for a full head of hair is a universal one, and androgenetic alopecia (male pattern baldness) is a common culprit. This study explores the efficacy of combining topical finasteride and minoxidil, two well-established hair loss treatments, in a novel approach. The researchers conducted a randomized, double-blind controlled trial to compare the effectiveness of a 0.25% finasteride/3% minoxidil solution against a 3% minoxidil solution alone. The results offer a glimmer of hope for those seeking to combat hair loss: the combination therapy proved significantly superior to minoxidil alone in promoting hair growth, as evidenced by increased hair density and diameter. Furthermore, the combined therapy demonstrated a minimal impact on plasma dihydrotestosterone (DHT) levels, a key hormone implicated in hair loss. This finding is especially reassuring, as it suggests a reduced potential for systemic side effects associated with finasteride.

A Powerful Duo: Finasteride and Minoxidil

The study concludes that topical finasteride and minoxidil work synergistically to promote hair growth in men with androgenetic alopecia. This finding may represent a significant advancement in hair loss treatment, offering a more effective and potentially safer alternative to oral finasteride. The combined solution was well tolerated, with no systemic adverse events reported. The study's results are encouraging, suggesting that this combination therapy could offer a viable option for men seeking to restore their hair.

Combatting Hair Loss: A New Hope

These findings present a ray of hope for individuals struggling with hair loss. This combined therapy, with its demonstrated effectiveness and safety profile, could offer a viable and potentially more effective solution to combatting androgenetic alopecia. It's important to consult with a healthcare professional to determine the most appropriate treatment option for your individual needs. Remember, a well-informed approach can help you confidently tackle hair loss and achieve your desired results.

Dr.Camel's Conclusion

Just as a thirsty camel stumbles upon a hidden oasis in the desert, individuals with androgenetic alopecia may find a solution in this novel combination therapy. The synergistic effect of topical finasteride and minoxidil, along with its well-tolerated nature, offers a beacon of hope for those seeking to restore their hair. This study, like a refreshing breeze in the desert, reminds us that innovation and progress are always possible in the field of medicine.

Date :
  1. Date Completed 2019-03-14
  2. Date Revised 2019-03-14
Further Info :

Pubmed ID

29972712

DOI: Digital Object Identifier

10.1111/jdv.15171

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.