Short-term efficacy and safety of rufinamide for Lennox-Gastaut syndrome.

Author: FukumuraShinobu, MinagawaKimio, TakayamaRumiko, WatanabeToshihide

Paper Details 
Original Abstract of the Article :
Objective: We examined the short-term efficacy and safety of rufinamide (RFN) in patients with Lennox-Gastaut syndrome (LGS). Methods: We performed a retrospective review of clinical records of patients with LGS who started RFN treatment between July 2013 and June 2014 at the Hokkaido Medical Center...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30010275

データ提供:米国国立医学図書館(NLM)

Rufinamide: A Potential Oasis for Lennox-Gastaut Syndrome

This research explores the effectiveness and safety of rufinamide (RFN) in treating Lennox-Gastaut Syndrome (LGS), a severe form of epilepsy that can cause a variety of seizures. Imagine a camel in a desert, facing sudden and unpredictable sandstorms. LGS is like that sandstorm, causing unpredictable seizures that can significantly disrupt the lives of those affected.

The researchers conducted a retrospective study involving 13 patients with LGS who were treated with RFN for three months. They evaluated the effectiveness of RFN in reducing seizure frequency and monitored any potential side effects.

The study found that RFN was effective in reducing the frequency of tonic seizures, a type of seizure that causes muscle stiffness. The researchers observed that while some patients achieved seizure-free periods (remission), others experienced a significant reduction in seizure frequency (response). This suggests that RFN can offer a degree of control over the sandstorms, allowing for a more stable and manageable journey for patients. The study also noted that RFN was well tolerated, with minimal side effects.

Rufinamide's Promise for Epilepsy Treatment

The study's results suggest that RFN could be a valuable treatment option for LGS, offering hope for a calmer and more predictable life for those affected by this challenging condition.

Living with Epilepsy: A Journey Through Sandstorms

Dr. Camel urges patients with LGS to work with their doctor to discuss the potential benefits and risks of RFN. While RFN may not completely eliminate seizures, it can help manage symptoms and improve quality of life. It's important to remember that managing epilepsy is like navigating a desert – there may be sandstorms, but with proper management, one can continue their journey with more stability and peace of mind.

Date :
  1. Date Completed 2018-08-28
  2. Date Revised 2018-08-28
Further Info :

Pubmed ID

30010275

DOI: Digital Object Identifier

30010275

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