In vitro effects of ciprofloxacin, levofloxacin and moxifloxacin on Mycobacterium tuberculosis isolates.

Author: Aktoğu ÖzkanSerir, BiçmenCan, EraçBayrı, ErmertcanŞafak, Hoşgör LimoncuMine, YılmazFethiye Ferda, ÇavuşoğluCengiz

Paper Details 
Original Abstract of the Article :
Increased tuberculosis prevalence, and isolation of multidrug resistant (MDR) Mycobacterium tuberculosis strains frequently as causative organisms from tuberculosis infections are resulted in increasing need of new anti-tuberculosis drugs. Nowadays, fluoroquinolones known to have fewer side effects ...See full text at original site
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引用元:
https://doi.org/10.5578/tt.58677

データ提供:米国国立医学図書館(NLM)

Ciprofloxacin, Levofloxacin, and Moxifloxacin: Examining Their Impact on Mycobacterium tuberculosis

The fight against tuberculosis (TB) is ongoing, particularly with the emergence of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis. This research investigates the in vitro effects of three fluoroquinolone antibiotics – ciprofloxacin, levofloxacin, and moxifloxacin – on both MDR and non-MDR strains of Mycobacterium tuberculosis. Fluoroquinolones are an important class of antibiotics with fewer side effects than some other TB drugs. This study explores their potential as first-line TB treatment, evaluating their in vitro activity against different strains of Mycobacterium tuberculosis.

Fluoroquinolones: A Promising Weapon Against TB

The study found that the fluoroquinolones tested exhibited significant in vitro activity against both MDR and non-MDR strains of Mycobacterium tuberculosis. These results suggest that fluoroquinolones could play a valuable role in treating TB, even as first-line therapy. The study provides compelling evidence for further investigation of the clinical potential of these antibiotics in combating TB.

New Hope for TB Treatment: A Desert Oasis in the Fight Against Disease

This research offers promising new avenues for fighting TB, a disease that continues to pose a significant threat globally. The results suggest that fluoroquinolones could be a powerful tool in our arsenal against TB, even in the face of drug resistance. This research is a reminder that the fight against TB is a continuous journey, with new discoveries and promising treatments emerging along the way. It is a reminder that with perseverance and innovation, we can overcome this formidable challenge.

Dr.Camel's Conclusion

This study provides hope for the development of new treatments for TB, a disease that has plagued humanity for centuries. The in vitro activity of fluoroquinolones against both MDR and non-MDR strains of Mycobacterium tuberculosis suggests that these antibiotics could be a valuable addition to our arsenal in the fight against this formidable foe.

Date :
  1. Date Completed 2018-10-22
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

30020039

DOI: Digital Object Identifier

10.5578/tt.58677

Related Literature

SNS
PICO Info
in preparation
Languages

English

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