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Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report.

Author: BlackneyKevin A, EdwardsDavid A, KamdarNirav V, LiuChang Amber

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes a 56-year-old man who developed opioid-induced constipation (OIC) and Ogilvie syndrome following lumbar decompression surgery. Treatment with methylnaltrexone led to an acute bowel perforation, highlighting the importance of careful monitoring and understanding the risks associated with this medication.
Paper Details　
Original Abstract of the Article :
Pain management with opioids is often limited by medication side effects. One of the most common and distressing side effects is opioid-induced constipation (OIC), a syndrome that is now getting significant national attention. We report the case of an opioid-dependent 56-year-old man who underwent l...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/30020107

データ提供：米国国立医学図書館（NLM）

Methylnaltrexone: A Potential Storm in the Desert of Opioid-Induced Constipation

Opioid-induced constipation (OIC), a common side effect of opioid medications, can be a distressing and uncomfortable experience. This case report delves into the potential risks associated with methylnaltrexone, a medication used to treat OIC.

The case report describes a patient who developed OIC and Ogilvie syndrome (a condition characterized by severe bowel obstruction) after undergoing surgery. The patient was treated with methylnaltrexone, but unfortunately, experienced an acute bowel perforation. This case report highlights the potential for serious complications associated with methylnaltrexone.

Methylnaltrexone: Navigating the Desert of Medication Risks

This case report serves as a reminder of the potential risks associated with any medication, including methylnaltrexone. It is essential to discuss your individual needs and risks with your healthcare provider before taking any medication.

Protecting Your Gut: Awareness and Careful Management

Opioid-induced constipation is a common side effect, and it's important to be aware of the potential risks and complications associated with medication used to treat it. This case report highlights the need for careful management and close monitoring of patients receiving methylnaltrexone.

Dr.Camel's Conclusion

Methylnaltrexone can be a valuable tool for managing opioid-induced constipation, but this case report underscores the importance of careful consideration and awareness of potential risks. Open communication with your healthcare provider is key to navigating the desert of medication risks and ensuring your health and well-being.

Date :
  1. Date Completed 2019-05-08
  2. Date Revised 2021-01-11
Further Info :

Pubmed ID

30020107

DOI: Digital Object Identifier

02054229-201901150-00004

SNS
PICO Info
in preparation
Languages

English

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