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[A New Twist on the Administration of Naldemedine for Opioid-Induced Constipation in an Outpatient].

Author: AsonumaShinichi, EmiYasunori, FujiiMisa, IkedaMunehiko, KajiwaraMie, KometaniTakuro, MoriMinami, NodaYoko, OchiaiToshiaki, ShikadaYasunori

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Opioid-induced constipation (OIC) is a common problem for cancer patients undergoing opioid treatment. Naldemedine has emerged as a new treatment option for OIC, but concerns about diarrhea remain. This report describes the use of naldemedine to alleviate diarrhea and improve bowel habits in outpatients with cancer.
Paper Details　
Original Abstract of the Article :
Opioid-induced constipation(OIC)occurs with high frequency in patients with cancer undergoing pain treatment using opioids. Osmotic or irritant laxatives are usually used to prevent OIC. Recently, naldemedine has become operational for OIC. Although naldemedine achieved the desired effect, diarrhea ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/30042276

データ提供：米国国立医学図書館（NLM）

Naldemedine: A New Approach to Opioid-Induced Constipation

Opioid-induced constipation (OIC) is a common and often frustrating side effect for cancer patients undergoing pain management with opioids. This research explores the use of naldemedine, a medication that specifically targets the opioid receptors in the gut, to alleviate constipation. While naldemedine has shown promise in treating OIC, the potential for diarrhea is a concern, based on clinical trial data.

This report highlights a unique application of naldemedine: using it to alleviate diarrhea in outpatient cancer patients experiencing OIC. The authors suggest that this approach could improve bowel function and overall quality of life for these patients.

Naldemedine: A Potential Solution for OIC

This case report offers a potentially valuable approach to managing OIC in cancer patients. The use of naldemedine to treat diarrhea, instead of preventing constipation, represents a novel and potentially impactful strategy.

Naldemedine: An Important Note for Cancer Patients

If you are a cancer patient undergoing pain management with opioids and experiencing OIC, it's essential to consult with your doctor. They can help you determine the best course of treatment, taking into account your individual needs and medical history.

Dr.Camel's Conclusion

This research, like a desert explorer finding a hidden spring, provides a new perspective on treating OIC in cancer patients. It's important to remember that a personalized approach, guided by medical professionals, is key to navigating the complex terrain of cancer care.

Date :
  1. Date Completed 2018-09-10
  2. Date Revised 2022-08-16
Further Info :

Pubmed ID

30042276

DOI: Digital Object Identifier

30042276

Related Literature

Article Analysis
・Effects of naldemedine
SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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