Simultaneous determination of ten nonsteroidal anti-inflammatory drugs from drinking water, surface water and wastewater using micro UHPLC-MS/MS with on-line SPE system.

Author: BobályBalázs, FeketeJenő, ImreTímea, MagdaBalázs, MártaZoltán, SzabóPál Tamás

Paper Details 
Original Abstract of the Article :
A simple, accurate and sensitive micro UHPLC-MS/MS method was developed and validated for the simultaneous determination of 10 nonsteroidal anti-inflammatory drugs (NSAIDs) from different environmental matrices. The micro LC ‒ on-line SPE method described in this study allowed to determine the...See full text at original site
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引用元:
https://doi.org/10.1016/j.jpba.2018.07.016

データ提供:米国国立医学図書館(NLM)

Simultaneous Determination of Nonsteroidal Anti-inflammatory Drugs in Water Samples

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve pain and inflammation, but their presence in environmental water sources can pose potential risks to human health. This study develops and validates a sensitive and reliable method for the simultaneous determination of 10 NSAIDs in drinking water, surface water, and wastewater using micro ultra-high performance liquid chromatography-tandem mass spectrometry (micro UHPLC-MS/MS) with an on-line solid-phase extraction (SPE) system. The researchers aim to provide a robust analytical tool for monitoring NSAID contamination in water samples.

A Sensitive and Reliable Method for NSAID Analysis

This study presents a novel and efficient method for the simultaneous determination of 10 NSAIDs in water samples. The researchers demonstrate the sensitivity, accuracy, and reliability of the micro UHPLC-MS/MS method with on-line SPE system, enabling the detection of NSAIDs at ultra-trace levels. The study highlights the method's ability to analyze samples directly after dilution with water, eliminating the need for complex and time-consuming off-line SPE procedures.

Protecting Water Quality and Public Health

This study emphasizes the importance of monitoring NSAID contamination in water sources to protect public health. The researchers develop and validate a sensitive and reliable method for the simultaneous determination of 10 NSAIDs in water samples, enabling the detection of these pharmaceuticals at ultra-trace levels. The study's findings highlight the crucial role of analytical chemistry in safeguarding water quality and ensuring the safety of our drinking water supplies. Just like a camel can survive in the desert by finding water sources, we need to ensure that our water supplies remain clean and safe for consumption.

Dr. Camel's Conclusion

This study presents a novel and efficient method for the simultaneous determination of 10 NSAIDs in water samples using micro UHPLC-MS/MS with on-line SPE system. The method's sensitivity, accuracy, and reliability enable the detection of NSAIDs at ultra-trace levels, providing a valuable tool for monitoring NSAID contamination in water sources and protecting public health. Just like a camel can survive in the desert by finding water sources, we need to ensure that our water supplies remain clean and safe for consumption.

Date :
  1. Date Completed 2018-12-11
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

30075399

DOI: Digital Object Identifier

10.1016/j.jpba.2018.07.016

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