Paper Details 
Original Abstract of the Article :
Renal cell carcinoma (RCC) is highly resistant to systemic chemotherapy, and historically a poor prognosis for metastatic disease has been reported, with a 5-year survival rate of <10%. Significant advances have been made in the last decade since the introduction of different tyrosine kinase inhibit...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.4103/ijc.IJC_380_17

データ提供:米国国立医学図書館(NLM)

First-line tyrosine kinase inhibitors in metastatic renal cell carcinoma: A regional cancer center experience

Oh, my dear! Renal cell carcinoma (RCC), a type of kidney cancer, has been a stubborn desert traveler, resistant to conventional chemotherapy. Like a lost camel in a vast desert, patients with metastatic RCC faced a grim prognosis with a 5-year survival rate less than 10%. But hold your camels! In the last decade, a new oasis of hope emerged with the introduction of tyrosine kinase inhibitors (TKIs), such as sunitinib, pazopanib, and sorafenib. These TKIs act like a compass, guiding the immune system to target and destroy the cancer cells. However, there's a twist in this desert tale. Even though TKIs have been used for a while, there wasn't much data available from India, a land with a unique medical landscape. This study dives into the Indian experience with TKI therapy, bringing us closer to understanding the effectiveness of this new treatment approach in a different geographical context.

Exploring the effectiveness of TKIs in India

This study sheds light on the effectiveness of TKI treatment for metastatic renal cell carcinoma in India. The results of this study provide valuable information about the use of TKIs in a specific geographical region, which can be crucial for future research and clinical practice.

Hope for metastatic renal cell carcinoma

This study brings hope to the desert of metastatic renal cell carcinoma. The use of TKIs in India demonstrates the potential for effective treatment and improved survival rates. As a researcher, I am excited about the possibilities that this new treatment avenue presents, especially in a diverse region like India.

Dr. Camel's Conclusion

This study is a beacon of hope in the vast desert of cancer research. It showcases the potential of TKIs in treating metastatic renal cell carcinoma, particularly in India. The results highlight the importance of exploring the effectiveness of existing treatments in diverse geographical contexts. By understanding the unique challenges and experiences in different regions, we can continue to advance the fight against cancer and improve the lives of patients worldwide.

Date :
  1. Date Completed 2018-10-31
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

30082547

DOI: Digital Object Identifier

10.4103/ijc.IJC_380_17

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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