Paper Details

  1. Home
  2. Paper Details

Maintenance Treatment and Survival in Patients With Myeloma: A Systematic Review and Network Meta-analysis.

Author: AttalMichel, BladéJoan, BoccadoroMario, BringhenSara, CairnsDavid A, DaviesFaith, Di RaimondoFrancesco, EvangelistaAndrea, GayFrancesca, HolsteinSarah A, HulinCyrille, HájekRoman, JacksonGraham, LahuertaJuan José, LeleuXavier, LiberatiAnna Marina, LudwigHeinz, MacroMargaret, MateosMaria-Victoria, McCarthyPhilip L, MoreauPhilippe, MorganGareth J, OffidaniMassimo, PanzaniUgo, PawlynCharlotte, RosiñolLaura, San-MiguelJesús, SonneveldPieter, SpadaStefano, SpencerAndrew, TerposEvangelos

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Lenalidomide maintenance is the best treatment option for newly diagnosed multiple myeloma based on progression-free survival and overall survival results.
Paper Details　
Original Abstract of the Article :
IMPORTANCE: Several trials demonstrated the impact of novel agent-based maintenance in newly diagnosed multiple myeloma (NDMM), but there is no current evidence demonstrating the superiority of one regimen over the other, owing to the lack of direct/indirect comparisons. OBJECTIVE: To analyze and c...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233774/

データ提供：米国国立医学図書館（NLM）

Optimizing Maintenance Treatment for Multiple Myeloma: A Comprehensive Analysis

The fight against cancer is a complex and demanding one, much like the harsh and unforgiving conditions of the desert. This study provides a comprehensive analysis of different maintenance treatment regimens for patients with newly diagnosed multiple myeloma (NDMM). The researchers used a network meta-analysis to compare the effectiveness of various maintenance regimens, including lenalidomide-based regimens, thalidomide-based regimens, and bortezomib-based regimens, in terms of progression-free survival (PFS) and overall survival (OS).

Lenalidomide Maintenance Emerges as a Leading Treatment Option

The study found that lenalidomide-based maintenance regimens consistently demonstrated the best outcomes for both PFS and OS, suggesting that lenalidomide may be a valuable treatment option for patients with NDMM. The researchers observed that lenalidomide-based maintenance significantly improved PFS and OS compared to other treatment options, highlighting its potential to enhance patient survival and quality of life.

Advancing Multiple Myeloma Treatment: A Collaborative Effort

This study highlights the importance of ongoing research and collaborative efforts in advancing multiple myeloma treatment. The researchers' findings provide valuable insights into the optimal use of maintenance therapies, paving the way for more effective and personalized treatment approaches. This research underscores the commitment of medical professionals to improving the lives of patients with multiple myeloma.

Dr.Camel's Conclusion

The journey to combat multiple myeloma is a long and challenging one, much like navigating the vast and unforgiving desert. This study provides a comprehensive analysis of different maintenance treatment regimens, offering valuable insights into the optimal use of these therapies. The researchers' findings highlight the importance of continued research and collaborative efforts in advancing multiple myeloma treatment, leading to better outcomes for patients and a brighter future for those affected by this disease.
Date :
  1. Date Completed 2019-10-09
  2. Date Revised 2019-10-10
Further Info :

Pubmed ID

30098165

DOI: Digital Object Identifier

PMC6233774

Related Literature

Article Analysis
・Effective treatment of multiple myeloma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.