Low-dose ketamine infusion reduces postoperative hydromorphone requirements in opioid-tolerant patients following spinal fusion: A randomised controlled trial.

Author: AtchabahianArthur, BoenigkKirsten, CuffGermaine E, EchevarriaGhislaine C, NisimovEmmanuel, WangJing, von Bergen GranellAnnelise E

Paper Details 
Original Abstract of the Article :
The current opioid epidemic highlights the urgent need for effective adjuvant therapies to complement postoperative opioid analgesia. Intra-operative ketamine infusion has been shown to reduce postoperative opioid consumption and improve pain control in opioid-tolerant patients after spinal fusion s...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1097/EJA.0000000000000877

データ提供:米国国立医学図書館(NLM)

Ketamine Infusion: A New Oasis in Postoperative Pain Management

The ongoing opioid epidemic continues to be a major challenge in healthcare, leading to a persistent search for alternative pain management strategies. This research explores the potential of ketamine, a versatile anesthetic agent, as an adjuvant therapy for postoperative pain management. The study focuses on opioid-tolerant patients undergoing spinal fusion surgery, a procedure that often involves significant postoperative pain. The authors conducted a randomized controlled trial, comparing the effects of low-dose ketamine infusion with standard postoperative opioid analgesia. Their results demonstrate a reduction in postoperative hydromorphone (a potent opioid) requirements in patients who received ketamine infusion. The study suggests that ketamine may play a valuable role in reducing opioid reliance and improving pain control, offering a promising avenue for safer and more effective pain management in the post-operative setting. However, the research also acknowledges the need for further investigations to assess the efficacy of ketamine in opioid-naïve patients, a population with distinct pain management needs.

A New Oasis in Pain Management: The Potential of Ketamine

The study's findings suggest that ketamine infusion can effectively reduce postoperative opioid requirements in opioid-tolerant patients, potentially mitigating the risks associated with long-term opioid use. Further research is needed to evaluate the efficacy of ketamine in other patient populations and to optimize its use in various surgical settings.

Navigating the Desert of Pain: Towards Safer and More Effective Relief

The research underscores the importance of exploring alternative approaches to pain management, particularly in the context of the opioid epidemic. By developing a multifaceted approach that incorporates both pharmacological and non-pharmacological interventions, healthcare professionals can work towards providing safer and more effective pain relief for patients. If you are experiencing persistent pain, consult with your doctor to discuss appropriate pain management options and develop a personalized treatment plan that addresses your individual needs and preferences.

Dr.Camel's Conclusion

The study suggests that ketamine infusion may hold the key to a more effective and safer approach to pain management, offering a potential oasis in the desert of chronic pain. Like a wise desert guide, ketamine may help us navigate the challenges of pain relief, leading us towards a brighter, more comfortable future.

Date :
  1. Date Completed 2019-12-16
  2. Date Revised 2019-12-17
Further Info :

Pubmed ID

30113350

DOI: Digital Object Identifier

10.1097/EJA.0000000000000877

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.