The effect of immunosuppressive agents on immunogenicity of pneumococcal vaccination: A systematic review and meta-analysis.

Author: GoorhuisAbraham, GrobuschMartin P, LangedijkAnnefleur C, SpijkerRené, de BreeGodelieve J, van AalstMariëlle

Paper Details 
Original Abstract of the Article :
Patients with a weakened immune system due to immunosuppressive treatment are at increased risk of infection with Streptococcus pneumoniae. Although pneumococcal vaccination is highly recommended for those patients, the effectiveness of pneumococcal vaccination in this population remains largely unk...See full text at original site
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引用元:
https://doi.org/10.1016/j.vaccine.2018.07.039

データ提供:米国国立医学図書館(NLM)

Immunosuppressive Agents and Pneumococcal Vaccination: A Balancing Act

This research delves into the complex world of [immunosuppressive agents] and their impact on [pneumococcal vaccination]. The study, like a camel navigating a treacherous desert, carefully examines the effectiveness of [pneumococcal vaccination] in patients undergoing [immunosuppressive treatment]. The researchers conducted a [systematic review and meta-analysis] to evaluate the [serologic response] to pneumococcal vaccination in patients taking various immunosuppressants such as [azathioprine, methotrexate, anti-Tumor Necrosis Factor α (TNFα), or rituximab]. This comprehensive analysis provides valuable insights into the effectiveness of vaccination in this vulnerable population.

Navigating the Desert of Immunosuppression

This research provides valuable guidance for clinicians managing patients undergoing [immunosuppressive treatment]. It's like navigating a desert; we must be mindful of the challenges faced by those with weakened immune systems. The study suggests that [pneumococcal vaccination] remains an important preventive measure for this population, even though the effectiveness may be influenced by the specific immunosuppressant used.

Protecting the Vulnerable: A Shared Responsibility

This research highlights the importance of [vaccination] in protecting those with weakened immune systems. It's like providing a protective oasis in a vast desert, ensuring the well-being of those who are most vulnerable. The findings emphasize the need for [close monitoring and appropriate vaccination strategies] for patients undergoing immunosuppressive treatment.

Dr.Camel's Conclusion

This research, like a camel caravan traversing a challenging desert, sheds light on the delicate balance between immunosuppressive treatment and pneumococcal vaccination. The findings emphasize the importance of individualized approaches to vaccination, ensuring optimal protection for patients who are most vulnerable. This research is a testament to the continuous pursuit of knowledge in the ever-evolving field of medicine.

Date :
  1. Date Completed 2019-02-14
  2. Date Revised 2019-02-15
Further Info :

Pubmed ID

30122649

DOI: Digital Object Identifier

10.1016/j.vaccine.2018.07.039

Related Literature

SNS
PICO Info
in preparation
Languages

English

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