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No difference between direct-acting antivirals for hepatitis C in hepatocellular carcinoma risk.

Author: BerryKristin, GreenPamela, IoannouGeorge N, MunElijah J

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

There were no significant differences in the risk of hepatocellular carcinoma (HCC) after antiviral treatment with different direct-acting antivirals (DAAs) for hepatitis C virus, suggesting that DAAs do not have direct carcinogenic effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND AIMS: It is unclear whether there are differences between direct-acting antivirals (DAAs) for hepatitis C virus in risk of hepatocellular carcinoma (HCC) after antiviral therapy. We aimed to compare different DAA regimens with respect to risk of de novo HCC following antiviral therapy...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/30142097

データ提供：米国国立医学図書館（NLM）

Direct-Acting Antivirals for Hepatitis C: No Difference in Hepatocellular Carcinoma Risk

This study investigates the potential link between different direct-acting antivirals (DAAs) for hepatitis C virus (HCV) and the risk of developing hepatocellular carcinoma (HCC) after antiviral therapy. The authors analyzed data from 33,137 patients who received DAA treatment for HCV and found no significant difference in the risk of HCC development between the four different DAA regimens studied. This finding suggests that DAAs do not have a direct carcinogenic effect.

DAAs and Hepatocellular Carcinoma: A Reassuring Finding

This study provides reassuring news for patients receiving DAA treatment for HCV. The results indicate that the choice of DAA regimen does not influence the risk of developing HCC. This finding is crucial for doctors and patients in making informed decisions about treatment options for HCV infection, with the confidence that different DAAs do not carry differing risks of HCC development.

Navigating Hepatitis C Treatment: A Clear Path Ahead

The study's findings contribute to a better understanding of HCV treatment and the potential risks associated with different DAA regimens. The authors emphasize the importance of individualized treatment plans, taking into account factors such as the stage of liver disease and other relevant medical history. This approach to HCV treatment, like a well-mapped route across the desert, allows for safe and effective treatment strategies for patients.

Dr.Camel's Conclusion

This study sheds light on the safety and efficacy of different DAA regimens for treating HCV infection. The authors' findings reassure patients and doctors alike, demonstrating that the choice of DAA does not alter the risk of developing HCC. The study is a valuable addition to the growing body of research on HCV treatment, providing a clearer path through the desert of HCV infection for patients seeking effective and safe treatment options.
Date :
  1. Date Completed 2019-04-09
  2. Date Revised 2020-01-01
Further Info :

Pubmed ID

30142097

DOI: Digital Object Identifier

NIHMS1503215

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Languages

English

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