Paper Details 
Original Abstract of the Article :
Cyclin-dependent kinase (CDK) 4/6 inhibitors have shown great results in numerous clinical trials and have improved the clinical outcome for patients with hormone-receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer significantly. To date, three CDK4/6 inhibito...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122233/

データ提供:米国国立医学図書館(NLM)

CDK4/6 Inhibitors: A Powerful Weapon Against Breast Cancer, But with Potential Side Effects

The fight against breast cancer continues to evolve with the development of new therapies. This study focuses on cyclin-dependent kinase (CDK) 4/6 inhibitors, a class of medications that have shown promising results in treating hormone-receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer. Researchers review the efficacy data for these inhibitors and discuss the associated adverse events, including hematological and nonhematological side effects. They provide guidance on monitoring patients and managing potential complications.

CDK4/6 Inhibitors: A Double-Edged Sword in Breast Cancer Treatment

This study highlights the effectiveness of CDK4/6 inhibitors in improving progression-free survival for patients with advanced breast cancer. However, it also acknowledges the potential for adverse events, including neutropenia, diarrhea, and QTc prolongation. The authors emphasize the importance of careful monitoring and appropriate management strategies to mitigate these side effects.

Managing Breast Cancer Treatment: A Balanced Approach

This study underscores the need for a balanced approach to breast cancer treatment. While CDK4/6 inhibitors offer a powerful tool in the fight against this disease, it's essential to be aware of potential side effects and have strategies in place for managing them. Just as a traveler in the desert must be prepared for both scorching sun and refreshing oases, breast cancer patients benefit from a treatment plan that acknowledges both the benefits and risks.

Dr.Camel's Conclusion

CDK4/6 inhibitors, like a powerful desert wind, can propel the fight against breast cancer. However, just as the desert can be unforgiving, it's important to be aware of the potential side effects. By staying vigilant and consulting with healthcare professionals, we can navigate this challenging journey with a balanced approach.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

30202447

DOI: Digital Object Identifier

PMC6122233

Related Literature

SNS
PICO Info
in preparation
Languages

English

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