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Sustained Viral Response in Genotype 4 Chronic Hepatitis C Virus-infected Children and Adolescents Treated With Sofosbuvir/Ledipasvir.
Author: AbdullatifHala, BaroudySherif, El-KaraksyHanaa, El-KoofyNehal, El-RazikyMona S, El-ShabrawiMortada, GhitaHaytham, GhobrialCarolyne, MogahedEngy Adel, OkashaSawsan
Original Abstract of the Article :
Recently, direct acting antivirals (DAAs), sofosbuvir (SOF) combined with ledipasvir (LED), were approved for treatment of hepatitis C virus (HCV)-infected children 12 years of age and older or weighting at least 35 kg for all HCV genotypes. The aim of this study was to assess the safety and efficac...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/MPG.0000000000002101
データ提供:米国国立医学図書館(NLM)
Sofosbuvir/Ledipasvir: A Powerful Weapon Against Genotype 4 HCV in Children and Adolescents
Hepatitis C virus (HCV) infection can be a challenging condition, particularly in children and adolescents. This research explores the efficacy and safety of the direct-acting antiviral (DAA) combination sofosbuvir (SOF) and ledipasvir (LED) in treating genotype 4 HCV-infected Egyptian children and adolescents. The study evaluates the sustained viral response (SVR) achieved with this treatment regimen, highlighting its potential for effectively managing HCV infection in this population. This research contributes to the growing body of knowledge on the treatment of HCV infection in children and adolescents, offering valuable insights into the effectiveness of DAAs in this population.
Sofosbuvir/Ledipasvir: A Beacon of Hope in the Desert of HCV Infection
This study demonstrates the significant efficacy of SOF/LED in achieving SVR in genotype 4 HCV-infected children and adolescents. The research highlights the potential of this treatment regimen to effectively clear the virus and potentially prevent the long-term complications associated with chronic HCV infection. This research offers a promising treatment option for children and adolescents with HCV infection, providing hope for a cure and a healthier future.
Finding a Cure: A Desert Oasis of Healing
Just as a desert traveler seeks a source of water, individuals with HCV infection seek a cure. This research highlights the importance of ongoing research and development of new and effective antiviral therapies to treat HCV infection, particularly in children and adolescents. This study encourages further research to expand our understanding of DAAs and optimize their use for achieving SVR in diverse patient populations, ultimately leading to a world free from the burden of HCV infection.
Dr.Camel's Conclusion
This study provides promising evidence for the efficacy and safety of SOF/LED in treating genotype 4 HCV infection in children and adolescents. The research highlights the potential of this treatment regimen to achieve SVR and potentially prevent the long-term complications associated with chronic HCV infection. This study underscores the importance of ongoing research and development of new and effective therapies for HCV infection, particularly in vulnerable populations like children and adolescents, ultimately leading to a world free from the burden of this debilitating disease.
Date :
- Date Completed 2019-11-25
- Date Revised 2020-12-09
Further Info :
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