Reproductive toxicology studies supporting the safety of molindone, a dopamine receptor antagonist.

Author: GanigerShivaputhrappa, GopalakrishnanGopakumar, WhiteTacey E K, YuChungping

Paper Details 
Original Abstract of the Article :
Label="BACKGROUND">An extended-release molindone (a dopamine D<sub>2</sub> and serotonin antagonist) is currently being developed as a novel treatment for impulsive aggression (IA) in patients optimally treated for ADHD. Oral Good Laboratory Practice reproductive toxicology studies (fertility and ea...See full text at original site
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引用元:
https://doi.org/10.1002/bdr2.1381

データ提供:米国国立医学図書館(NLM)

Molindone: A Promising Treatment for Impulsive Aggression?

Impulsive aggression (IA) is a challenging condition that can significantly impact individuals' lives. This study explores the potential of extended-release molindone, a dopamine and serotonin antagonist, as a novel treatment for IA in patients with ADHD. The authors conducted a comprehensive series of reproductive toxicology studies to assess the safety of molindone in various stages of development.

A Novel Approach to Impulsive Aggression: Exploring the Potential of Molindone

The study demonstrates that molindone holds promise as a treatment for IA in patients with ADHD. The positive results of the reproductive toxicology studies indicate that molindone exhibits a favorable safety profile, supporting its further development as a therapeutic agent. This research opens up new avenues for addressing IA and improving the well-being of individuals affected by this challenging condition.

A New Oasis in the Desert of Treatment Options: Navigating the Potential of Molindone

The study provides valuable information for clinicians and researchers exploring new treatments for impulsive aggression. It highlights the importance of conducting rigorous safety studies to ensure the well-being of patients. While molindone holds promise, further research is needed to fully understand its long-term effects and optimize its use in clinical practice.

Dr. Camel's Conclusion

The desert of impulsive aggression is a harsh and unforgiving place. This study offers a promising oasis in the form of molindone. While further exploration is needed, this research provides a hopeful glimpse into the future of IA treatment. It reminds us that even in the most challenging conditions, there's always a chance for a new sunrise.

Date :
  1. Date Completed 2019-06-14
  2. Date Revised 2019-06-14
Further Info :

Pubmed ID

30230712

DOI: Digital Object Identifier

10.1002/bdr2.1381

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Languages

English

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