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Combined effects of Lenvatinib and iodine-131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress.
Author: HeSaifei, NiJing, WangGuoyu, XiaWei, YeYing, ZhuangJuhua
Original Abstract of the Article :
Nasopharyngeal carcinoma (NPC) is a type of malignant tumor characterized by high invasiveness, metastatic potential and worldwide incidence among patients with head and neck cancer. It has previously been demonstrated that Lenvatinib (LEB) is an efficient anti-cancer agent by multi-targeting of tyr...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143866/
データ提供:米国国立医学図書館(NLM)
Targeting Nasopharyngeal Carcinoma: A Multi-pronged Approach
Nasopharyngeal carcinoma (NPC), a type of head and neck cancer, can be a formidable foe, like a sandstorm sweeping across the desert of health. This study delves into the world of cancer treatment, exploring the potential of a combined therapy using Lenvatinib (LEB) and iodine-131 (I-131) to fight NPC. It's like using a combination of powerful desert winds to control a raging sandstorm.
The researchers investigated the combined effects of LEB and I-131 on NPC cells. They found that this combination therapy was more effective than either treatment alone in inhibiting tumor growth and promoting apoptosis (cell death). It's like using a multi-pronged approach to combat a sandstorm, creating a shield to protect the oasis.
The study also revealed that the combined therapy triggered endoplasmic reticulum (ER) stress in NPC cells. This finding offers insights into the mechanism of action of this treatment approach. It's like understanding the intricate dynamics of the desert winds and using that knowledge to create a more effective defense against sandstorms.
The Promise of Combined Therapy
This study suggests that combining LEB and I-131 could be a promising treatment strategy for NPC. It's like finding a new and powerful weapon in the fight against cancer.
The Importance of Research and Innovation
This study highlights the need for ongoing research and innovation in cancer treatment. It's like continually exploring the desert for new resources and strategies to combat the challenges of disease.
Dr.Camel's Conclusion
This study offers hope for patients with nasopharyngeal carcinoma. It's like finding a new oasis in the desert of cancer treatment, providing a powerful tool for combating this challenging disease. The study underscores the importance of research and innovation in finding new and effective treatments for cancer.
Date :
- Date Completed n.d.
- Date Revised 2020-10-01
Further Info :
Related Literature
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