Patient-reported outcomes in patients with relapsing forms of MS switching to teriflunomide from other disease-modifying therapies: Results from the global Phase 4 Teri-PRO study in routine clinical practice.

Author: , BenamorMyriam, CavalierSteve, CoylePatricia K, EdwardsKeith R, GoldRalf, KhatriBhupendra, Meca-LallanaJosé E, RobinsonMiqun, RufiPascal, ThangaveluKarthinathan

Paper Details 
Original Abstract of the Article :
Patient-reported outcomes (PROs) can assist clinicians in understanding the impact of disease-modifying therapy (DMT) on the daily lives of patients with multiple sclerosis (MS). With an increased number of DMTs becoming available, patients are now switching treatments more frequently in clinical pr...See full text at original site
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引用元:
https://doi.org/10.1016/j.msard.2018.09.017

データ提供:米国国立医学図書館(NLM)

Switching Gears: Evaluating the Impact of Teriflunomide on MS Patients

The world of multiple sclerosis (MS) treatment is a vast desert, with many different therapies for patients to navigate. This research delves into the impact of switching to teriflunomide, a therapy often used in the treatment of relapsing forms of MS, from other disease-modifying therapies (DMTs). The study, Teri-PRO, used a global, multicenter, open-label, phase 4 design to capture real-world data in routine clinical practice. The researchers were particularly interested in how switching to teriflunomide affected patient-reported outcomes (PROs), which can provide valuable insights into how a therapy impacts a patient's daily life.

Teriflunomide: A New Oasis in the MS Desert?

The study found that switching to teriflunomide led to statistically and clinically significant improvements in treatment satisfaction compared to other DMTs. This is a significant finding as treatment satisfaction is a crucial factor in a patient's overall well-being and adherence to their therapy. This is akin to finding a refreshing oasis in the midst of a challenging desert journey.

Navigating the MS Treatment Landscape: What Does This Mean for Patients?

This study offers a glimpse into the potential benefits of teriflunomide as a treatment option for MS patients who are considering switching therapies. It suggests that teriflunomide can be a valuable tool in managing the challenges of MS, potentially offering a better quality of life. However, it is important to consult with a healthcare professional to determine the best treatment plan for each individual.

Dr. Camel's Conclusion

This research provides a valuable roadmap for navigating the complex treatment landscape of multiple sclerosis. It highlights the importance of considering patient-reported outcomes in evaluating the efficacy of therapies. The study emphasizes the need for ongoing research to better understand the nuances of DMT switching and its impact on patients' lives.

Date :
  1. Date Completed 2019-02-28
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

30273841

DOI: Digital Object Identifier

10.1016/j.msard.2018.09.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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