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Interventions for reducing inflammation in familial Mediterranean fever.
Author: LiYouping, WuBin, XuTing, YinXi
Original Abstract of the Article :
Familial Mediterranean fever, a hereditary auto-inflammatory disease, mainly affects ethnic groups living in the Mediterranean region. Early studies reported colchicine as a potential drug for preventing attacks of familial Mediterranean fever. For those people who are colchicine-resistant or intole...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517233/
データ提供:米国国立医学図書館(NLM)
Familial Mediterranean Fever: A Desert of Inflammation
Familial Mediterranean fever (FMF), an inherited auto-inflammatory disease, can be a challenging condition, leaving sufferers feeling trapped in a desert of painful inflammation. This review summarizes the current understanding of FMF, highlighting the various treatment options available, including the traditional use of colchicine and newer therapies that target specific inflammatory pathways.
Colchicine and Beyond: A Variety of Oasis in the Desert of FMF
The review emphasizes the role of colchicine as a mainstay of treatment for FMF, effectively reducing the frequency and severity of attacks. However, for those who are intolerant or resistant to colchicine, the review explores a range of alternative medications, including rilonacept, anakinra, canakinumab, etanercept, infliximab, thalidomide, and interferon-alpha. These newer therapies provide a diverse array of options for managing FMF, offering hope for a more comfortable life for those living with this condition.
Living with FMF: Finding a Path to Relief
This review provides a comprehensive overview of the treatment options available for FMF, highlighting the importance of early diagnosis and the value of personalized treatment approaches. Understanding the diverse range of therapies available can empower individuals with FMF to find a path towards relief and a better quality of life, transforming the desert of their illness into a more manageable landscape.
Dr.Camel's Conclusion
This review offers a valuable guide for clinicians and patients navigating the complex landscape of familial Mediterranean fever. It highlights the role of colchicine as a mainstay of treatment, but also explores the potential of newer therapies for those who are intolerant or resistant to this medication. By understanding the diverse range of available options, individuals with FMF can find a path towards relief and a better quality of life.
Date :
- Date Completed 2019-02-01
- Date Revised 2022-08-30
Further Info :
Related Literature
English
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