Interventions for reducing inflammation in familial Mediterranean fever.

Author: LiYouping, WuBin, XuTing, YinXi

Paper Details 
Original Abstract of the Article :
Familial Mediterranean fever, a hereditary auto-inflammatory disease, mainly affects ethnic groups living in the Mediterranean region. Early studies reported colchicine as a potential drug for preventing attacks of familial Mediterranean fever. For those people who are colchicine-resistant or intole...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517233/

データ提供:米国国立医学図書館(NLM)

Familial Mediterranean Fever: A Desert of Inflammation

Familial Mediterranean fever (FMF), an inherited auto-inflammatory disease, can be a challenging condition, leaving sufferers feeling trapped in a desert of painful inflammation. This review summarizes the current understanding of FMF, highlighting the various treatment options available, including the traditional use of colchicine and newer therapies that target specific inflammatory pathways.

Colchicine and Beyond: A Variety of Oasis in the Desert of FMF

The review emphasizes the role of colchicine as a mainstay of treatment for FMF, effectively reducing the frequency and severity of attacks. However, for those who are intolerant or resistant to colchicine, the review explores a range of alternative medications, including rilonacept, anakinra, canakinumab, etanercept, infliximab, thalidomide, and interferon-alpha. These newer therapies provide a diverse array of options for managing FMF, offering hope for a more comfortable life for those living with this condition.

Living with FMF: Finding a Path to Relief

This review provides a comprehensive overview of the treatment options available for FMF, highlighting the importance of early diagnosis and the value of personalized treatment approaches. Understanding the diverse range of therapies available can empower individuals with FMF to find a path towards relief and a better quality of life, transforming the desert of their illness into a more manageable landscape.

Dr.Camel's Conclusion

This review offers a valuable guide for clinicians and patients navigating the complex landscape of familial Mediterranean fever. It highlights the role of colchicine as a mainstay of treatment, but also explores the potential of newer therapies for those who are intolerant or resistant to this medication. By understanding the diverse range of available options, individuals with FMF can find a path towards relief and a better quality of life.

Date :
  1. Date Completed 2019-02-01
  2. Date Revised 2022-08-30
Further Info :

Pubmed ID

30338514

DOI: Digital Object Identifier

PMC6517233

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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