Therapeutic effects of lenvatinib in combination with rAd-p53 for the treatment of non-small cell lung cancer.

Author: JiangAiying, SunZhe, WangMinghuan, YaoHuixin, YuRenzhi, ZhuXiuli

Paper Details 
Original Abstract of the Article :
The aim of the present study was to analyze the effects of the combined treatment of lenvatinib and adenoviral delivered p53 gene (rAd-p53) on non-small cell lung cancer (NSCLC) cells and a total of 120 patients with NSCLC. The therapeutic effects of gene therapy of rAd-p53 and target therapy of Len...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202525/

データ提供:米国国立医学図書館(NLM)

A Synergistic Approach to NSCLC: Combining Lenvatinib and rAd-p53

Non-small cell lung cancer (NSCLC), a formidable foe in the battle against cancer, presents a challenge to researchers seeking effective treatments. This research explores a novel approach to combating NSCLC by combining the targeted therapy lenvatinib with adenoviral delivered p53 gene (rAd-p53). This strategy is like a two-pronged attack on a desert fortress, simultaneously targeting multiple pathways to weaken the cancer cells.

A Promising Combination: Lenvatinib and rAd-p53

The study demonstrates that combining lenvatinib and rAd-p53 significantly inhibited NSCLC cell growth, migration, and invasion, while promoting apoptosis. It’s like a sandstorm in the desert, effectively disrupting the cancer cells’ defenses. This promising strategy shows potential for improving the treatment of NSCLC patients, offering a glimmer of hope in the ongoing battle against this disease.

A New Weapon in the Arsenal Against NSCLC

The study's findings suggest that the combined treatment of lenvatinib and rAd-p53 could provide a new and effective therapeutic approach for NSCLC patients. It’s like discovering a hidden spring in the desert, offering a new source of hope and potentially leading to improved outcomes for those facing this devastating disease.

Dr.Camel's Conclusion

The research highlights the potential of a combined approach to fighting NSCLC. The synergistic effects of lenvatinib and rAd-p53 offer a promising avenue for improving treatment outcomes, providing a glimmer of hope in the fight against this challenging disease.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

30405797

DOI: Digital Object Identifier

PMC6202525

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Languages

English

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