Paper Details 
Original Abstract of the Article :
Chemotherapy-induced alopecia (CIA) is a common side effect of conventional chemotherapy and represents a major problem in clinical oncology. Even months after the end of chemotherapy, many cancer patients complain of hair loss, a condition that is psychologically difficult to manage. CIA disturbs s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267362/

データ提供:米国国立医学図書館(NLM)

Annurca Apple Polyphenols: A Potential Boon for Hair Loss

The world of hair loss research is a bustling desert, with researchers constantly searching for new oases of hope for those struggling with this common condition. This particular study focuses on the potential of polyphenols, those beneficial compounds found in plants, as a natural remedy for hair loss caused by chemotherapy. The researchers employed a combination of in vitro and in vivo experiments to explore the effects of Annurca apple polyphenolic extract (AAE) on hair follicles. Their findings indicate that AAE exhibits hair growth promoting activity and could potentially be a safe alternative to conventional therapies.

A Potential New Weapon Against Chemotherapy-Induced Alopecia

The researchers discovered that AAE effectively protects hair follicles from the damaging effects of taxanes, a common class of chemotherapy drugs. This is significant, as it suggests that AAE could help mitigate the debilitating side effect of hair loss associated with cancer treatment. Furthermore, AAE's unique mechanism of action makes it particularly intriguing. It boosts energy production within hair follicles through a process called β-oxidation, which results in increased keratin production. This means that AAE could not only prevent hair loss but also promote hair growth.

A Natural Approach to Hair Health

While conventional treatments for hair loss often come with a variety of potential side effects, this study points towards a natural and potentially safer approach. The researchers' findings suggest that AAE could be a valuable tool for managing chemotherapy-induced alopecia. However, further research is crucial to confirm these findings and establish the optimal dosage and application methods for AAE.

Dr. Camel's Conclusion

These findings are truly exciting! It seems like Mother Nature might hold the key to tackling hair loss, even in the face of challenging treatments like chemotherapy. The potential of polyphenols, like those found in Annurca apples, to promote hair growth is a desert oasis of hope for many. However, as with any scientific discovery, further research is essential to ensure the safety and efficacy of AAE before it can be widely used.

Date :
  1. Date Completed 2019-01-28
  2. Date Revised 2019-01-28
Further Info :

Pubmed ID

30463345

DOI: Digital Object Identifier

PMC6267362

SNS
PICO Info
in preparation
Languages

English

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