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The effects of S-adenosyl-L-methionine-vitamin B complex on mild and moderate depressive symptoms.

Author: AgicA, DjokicG, DjordjevicV, DjukicDejanovic, KorcokD, RankovicA

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

SAMe-vitamin B complex supplementation for three months was effective in improving mild to moderate depressive symptoms compared to placebo.
Paper Details　
Original Abstract of the Article :
BACKGROUND: S-adenosyl-L-methionine (SAMe) acts as a methyl donor, with dopamine, norepinephrine, and serotonin elevating properties, with potential antidepressant effects. In this study, we evaluated the efficacy of SAMe-vitamin B complex supplement for improving mild and moderate depressive sympto...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247995/

データ提供：米国国立医学図書館（NLM）

S-Adenosyl-L-methionine-Vitamin B Complex: An Oasis in the Desert of Depression

The world of mental health is a vast and complex desert, where researchers are constantly searching for effective treatments for mood disorders. This study explores the potential benefits of S-adenosyl-L-methionine (SAMe)-vitamin B complex supplementation for improving mild and moderate depressive symptoms.

The researchers conducted a randomized controlled trial to evaluate the efficacy of SAMe-vitamin B complex compared to a placebo in patients diagnosed with depression. They assessed the severity of depressive symptoms using the Hamilton Depression rating scale (HAMD17), Clinical Global Impression-Severity scale (CGI-S), and Clinical Global Impression-Improvement scale (CGI-I).

SAMe-Vitamin B Complex: A Potential Oasis in the Desert of Depression

The results of this study are promising, showing that SAMe-vitamin B complex supplementation can be an effective treatment for mild to moderate depressive symptoms. The researchers found a statistically significant difference between the study group and the control group in terms of HAMD17 and CGI-S scores, indicating a significant improvement in depressive symptoms in the group receiving SAMe-vitamin B complex.

Navigating the Sand Dunes of Depression Treatment

This research offers a potential new avenue for treating mild to moderate depression, a condition that affects millions of people worldwide. The researchers believe that SAMe-vitamin B complex supplementation could be a valuable addition to the existing treatment options for depression.

Dr.Camel's Conclusion

This study suggests that SAMe-vitamin B complex could be a valuable tool in the fight against depression. The researchers' findings offer hope for patients seeking relief from this debilitating condition, reminding us that even in the vast and challenging desert of mental health, there are oases of effective treatments waiting to be discovered.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

30479476

DOI: Digital Object Identifier

PMC6247995

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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