Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial.

Author: BelluLuisa, BrandesAlba Ariela, DanieleBruno, De SalvoGian Luca, EoliMarica, FaediMarina, FarinaMiriam, GardimanMarina Paola, IndraccoloStefano, LolliIvan, LombardiGiuseppe, MagniGiovanna, PaceAndrea, PambukuArdi, PasqualettiFrancesco, RizzatoSimona, RudàRoberta, SoffiettiRiccardo, ZagonelVittorina

Paper Details 
Original Abstract of the Article :
Glioblastoma is a highly vascularised tumour and there are few treatment options after disease recurrence. Regorafenib is an oral multikinase inhibitor of angiogenic, stromal, and oncogenic receptor tyrosine kinases. We aimed to assess the efficacy and safety of regorafenib in the treatment of recur...See full text at original site
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引用元:
https://doi.org/10.1016/S1470-2045(18)30675-2

データ提供:米国国立医学図書館(NLM)

Glioblastoma: Battling the Desert Storm of Cancer

Glioblastoma, a particularly aggressive brain tumor, is like a relentless sandstorm, sweeping through the delicate landscape of the brain. This study examines the potential of regorafenib, a multikinase inhibitor, in combating this formidable foe. The authors embarked on a rigorous clinical trial, carefully evaluating the efficacy and safety of regorafenib in treating recurrent glioblastoma. Their findings offer a glimmer of hope in the fight against this devastating disease, suggesting that regorafenib could potentially slow the progression of glioblastoma and improve outcomes for patients. This research, like a desert oasis, provides a potential refuge for those battling this challenging disease.

Regorafenib: A Potential Weapon Against Glioblastoma

The study's findings suggest that regorafenib, a multikinase inhibitor, may offer a new weapon in the fight against recurrent glioblastoma. The authors highlight the potential of this drug to slow tumor growth and improve outcomes for patients. This discovery, like a precious spring in the desert, provides a glimmer of hope for those battling this aggressive cancer. Further research is needed to fully evaluate the long-term effectiveness of regorafenib in treating glioblastoma, but this study offers a promising step towards a brighter future for patients.

Navigating the Desert of Cancer Treatment: Hope and Resilience

This study underscores the importance of ongoing research and innovation in the fight against cancer, particularly glioblastoma. The authors' findings highlight the potential of targeted therapies like regorafenib to improve outcomes for patients. Remember, my dear friends, in the desert of cancer treatment, hope and resilience are essential. While the journey may be challenging, advancements in research, coupled with unwavering optimism, offer a path towards a healthier future.

Dr.Camel's Conclusion

This study provides a beacon of hope in the battle against glioblastoma, highlighting the potential of regorafenib in slowing tumor growth and improving patient outcomes. While the journey through the desert of cancer treatment is challenging, research continues to offer promising avenues for a healthier future.

Date :
  1. Date Completed 2020-04-16
  2. Date Revised 2022-02-04
Further Info :

Pubmed ID

30522967

DOI: Digital Object Identifier

10.1016/S1470-2045(18)30675-2

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English

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