Diphenhydramine and QT prolongation - A rare cardiac side effect of a drug used in common practice.

Author: RaghuvirRashmi, ShahAditya, YousufTariq, ZaidiAli, ZiffraJeffrey

Paper Details 
Original Abstract of the Article :
There have been few cases in recent times where QT interval prolongation has been studied with regards to the use of diphenhydramine. We present a case of a patient who presented because of shortness of breath and needed emergent hemodialysis; during the course of which he developed prolonged QT int...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281831/

データ提供:米国国立医学図書館(NLM)

Diphenhydramine and QT Prolongation: A Hidden Cardiac Risk

The world of [cardiology] is constantly uncovering new insights into the delicate balance of our heart's rhythm. This case report explores the potential cardiac side effect of diphenhydramine, a common antihistamine often used to treat allergies and itching. The authors describe a patient who developed a prolonged QT interval, a potentially life-threatening condition, while receiving diphenhydramine. This case highlights the importance of considering even commonly used medications' potential side effects, especially in vulnerable patient populations like those with end-stage renal disease.

Diphenhydramine: A Double-Edged Sword?

Diphenhydramine, a seemingly harmless over-the-counter medication, can have potentially serious consequences. The study's findings raise concerns about the potential cardiac risks associated with diphenhydramine use, particularly in individuals with pre-existing heart conditions or those receiving other medications that can prolong the QT interval. The study emphasizes the need for careful monitoring and consideration of alternative treatments when using diphenhydramine.

Heart Health: A Matter of Awareness

This research reminds us that even seemingly safe medications can carry unexpected risks. It's crucial to be aware of potential side effects and to consult with a healthcare professional before taking any medications, especially those that could affect our heart's rhythm. We should remember that our health is a delicate ecosystem, and even a small change can have a significant impact.

Dr. Camel's Conclusion

Diphenhydramine, like a mirage in the desert, may seem like a simple solution, but it can also hold hidden dangers. This research underscores the importance of considering the potential risks of even commonly used medications. It's a reminder that we should be mindful of our heart's delicate balance and seek guidance from medical professionals when navigating the vast landscape of medications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

30546575

DOI: Digital Object Identifier

PMC6281831

Related Literature

SNS
PICO Info
in preparation
Languages

English

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