Influence of Polypharmacy on the Effectiveness and Safety of Rivaroxaban Versus Warfarin in Patients With Nonvalvular Atrial Fibrillation.

Author: BakerWilliam L, BunzThomas J, ColemanCraig I, ErikssonDaniel, MartinezBrandon K, MeineckeAnna-Katharina, SoodNitesh A

Paper Details 
Original Abstract of the Article :
Patients with nonvalvular atrial fibrillation (NVAF) often have multiple comorbidities requiring concomitant medications in addition to their oral anticoagulant (OAC). The objective of this study was to evaluate the impact of polypharmacy on the effectiveness and safety of rivaroxaban versus warfari...See full text at original site
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引用元:
https://doi.org/10.1002/phar.2213

データ提供:米国国立医学図書館(NLM)

Polypharmacy and Anticoagulation: Navigating a Complex Terrain in Atrial Fibrillation Management

Atrial fibrillation (AFib) is a common heart rhythm disorder that can feel like a chaotic desert of irregular heartbeats. This study delves into the complex interplay between polypharmacy (the use of multiple medications) and anticoagulation in patients with AFib. The researchers compared the effectiveness and safety of rivaroxaban, a newer anticoagulant, with warfarin, a more traditional anticoagulant, in patients taking multiple medications.

Rivaroxaban: A Potential Solution for Managing Polypharmacy in AFib

This study reveals that rivaroxaban may be a more effective and safer anticoagulant than warfarin in patients with AFib who are also taking multiple medications. The researchers found that rivaroxaban was associated with a lower risk of stroke and bleeding compared to warfarin, particularly in patients on polypharmacy.

Navigating the Desert of Polypharmacy: Considerations for AFib Management

This research highlights the challenges of managing AFib in patients taking multiple medications. The findings suggest that rivaroxaban may offer a safer and more effective anticoagulation option for these patients. However, it is crucial to consult with a healthcare professional to determine the most appropriate anticoagulant for individual circumstances.

Dr.Camel's Conclusion

This study emphasizes the need for careful consideration when managing AFib in patients on polypharmacy. Just like a skilled guide navigating a complex desert landscape, healthcare professionals must carefully select the best medications for individual patients to ensure their safety and well-being.

Date :
  1. Date Completed 2020-03-25
  2. Date Revised 2020-03-25
Further Info :

Pubmed ID

30597611

DOI: Digital Object Identifier

10.1002/phar.2213

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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