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Comparison of anti-inflammatory effects of rivaroxaban vs. dabigatran in patients with non-valvular atrial fibrillation (RIVAL-AF study): multicenter randomized study.
Author: ArakawaKentaro, EndoTsutomu, FukuiKazuki, HimenoHideo, IshikawaToshiyuki, KikuchiShinnosuke, KimuraKazuo, KobayashiSyunichi, MochidaYasuyuki, MoritaYukiko, OkudaJun, SakamakiKentaro, SawadaReimin, ShigemasaTomohiko, ShimizuMakoto, SuganoTeruyasu, TakamuraTakeshi, TamuraKouichi, TsukaharaKengo, TsunematsuTakashi
Original Abstract of the Article :
Some experimental studies have shown that direct oral anticoagulants (DOACs) have anti-inflammatory effects. However, the interval changes in inflammatory markers in patients with non-valvular atrial fibrillation (AF) who receive DOACs remain unknown. Between July 2013 and April 2014, a total of 187...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s00380-018-01324-7
データ提供:米国国立医学図書館(NLM)
The Silent War: Inflammation and Atrial Fibrillation
The heart is like a powerful camel, carrying us through life's journey. But sometimes, this mighty beast can become irregular, causing a condition known as atrial fibrillation. This research delves into the intricate world of inflammation, a silent storm that can affect our health in unexpected ways. The researchers were curious about how two common medications, rivaroxaban and dabigatran, might affect inflammation in patients with atrial fibrillation.
Investigating the Sands of Inflammation
Their study, like a meticulous exploration of a vast desert, involved analyzing various inflammatory markers in the blood. The results showed that while there were some subtle differences, neither medication significantly reduced inflammation. This is like finding that while the desert landscape might change slightly, the overall terrain remains the same.
Navigating the Desert of Heart Health
This study is a valuable reminder that while we can manage atrial fibrillation, the underlying causes of inflammation need further investigation. Like a desert traveler, we need to be aware of the hidden dangers lurking beneath the surface and continue to seek ways to improve our heart health.
Dr. Camel's Conclusion
This research sheds light on the complex interplay between inflammation and atrial fibrillation. It reminds us that the journey to heart health is ongoing and requires a constant exploration of the vast desert of medical knowledge.
Date :
- Date Completed 2019-12-03
- Date Revised 2020-02-25
Further Info :
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