Comparison of anti-inflammatory effects of rivaroxaban vs. dabigatran in patients with non-valvular atrial fibrillation (RIVAL-AF study): multicenter randomized study.

Author: ArakawaKentaro, EndoTsutomu, FukuiKazuki, HimenoHideo, IshikawaToshiyuki, KikuchiShinnosuke, KimuraKazuo, KobayashiSyunichi, MochidaYasuyuki, MoritaYukiko, OkudaJun, SakamakiKentaro, SawadaReimin, ShigemasaTomohiko, ShimizuMakoto, SuganoTeruyasu, TakamuraTakeshi, TamuraKouichi, TsukaharaKengo, TsunematsuTakashi

Paper Details 
Original Abstract of the Article :
Some experimental studies have shown that direct oral anticoagulants (DOACs) have anti-inflammatory effects. However, the interval changes in inflammatory markers in patients with non-valvular atrial fibrillation (AF) who receive DOACs remain unknown. Between July 2013 and April 2014, a total of 187...See full text at original site
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引用元:
https://doi.org/10.1007/s00380-018-01324-7

データ提供:米国国立医学図書館(NLM)

The Silent War: Inflammation and Atrial Fibrillation

The heart is like a powerful camel, carrying us through life's journey. But sometimes, this mighty beast can become irregular, causing a condition known as atrial fibrillation. This research delves into the intricate world of inflammation, a silent storm that can affect our health in unexpected ways. The researchers were curious about how two common medications, rivaroxaban and dabigatran, might affect inflammation in patients with atrial fibrillation.

Investigating the Sands of Inflammation

Their study, like a meticulous exploration of a vast desert, involved analyzing various inflammatory markers in the blood. The results showed that while there were some subtle differences, neither medication significantly reduced inflammation. This is like finding that while the desert landscape might change slightly, the overall terrain remains the same.

Navigating the Desert of Heart Health

This study is a valuable reminder that while we can manage atrial fibrillation, the underlying causes of inflammation need further investigation. Like a desert traveler, we need to be aware of the hidden dangers lurking beneath the surface and continue to seek ways to improve our heart health.

Dr. Camel's Conclusion

This research sheds light on the complex interplay between inflammation and atrial fibrillation. It reminds us that the journey to heart health is ongoing and requires a constant exploration of the vast desert of medical knowledge.

Date :
  1. Date Completed 2019-12-03
  2. Date Revised 2020-02-25
Further Info :

Pubmed ID

30599063

DOI: Digital Object Identifier

10.1007/s00380-018-01324-7

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English

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