Therapeutic thrombocytapheresis for extreme thrombocytosis after chemotherapy in essential thrombocytosis.

Author: AlbaCristina, Almeida-DiasRaquel, CidJoan, GarroteMarta, LozanoMiquel, MustielesMaria-Jesús

Paper Details 
Original Abstract of the Article :
Essential thrombocytosis (ET) is a chronic myeloproliferative neoplasm characterized by the presence of thrombocytosis and it can be complicated by thrombotic and/or hemorrhagic events. Treatment options include low-dose aspirin and cytoreductive agents such as hydroxyurea. In cases of extreme throm...See full text at original site
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引用元:
https://doi.org/10.1002/jca.21683

データ提供:米国国立医学図書館(NLM)

Therapeutic Thrombocytapheresis: A Powerful Tool for Managing Extreme Thrombocytosis

Navigating the world of blood disorders can be challenging, and patients often find themselves facing a complex array of treatment options. This case report sheds light on a specific challenge: extreme thrombocytosis, a condition characterized by an abnormally high platelet count. This condition can be a serious concern, as it can lead to an increased risk of blood clots. The researchers present a case of a patient diagnosed with essential thrombocytosis (ET), a chronic myeloproliferative neoplasm, who experienced an extreme rise in platelet count after undergoing chemotherapy for acute myeloid leukemia. They successfully employed therapeutic thrombocytapheresis, a procedure that removes excess platelets from the blood, to manage the patient's condition.

Thrombocytapheresis: A Safe and Efficient Treatment Option

The researchers highlight the safety and efficacy of therapeutic thrombocytapheresis in managing extreme thrombocytosis. They demonstrate that the procedure can effectively reduce platelet count to safe levels, providing relief to patients experiencing this serious condition. In the case presented, two thrombocytapheresis procedures were performed, successfully decreasing the patient's platelet count from a dangerously high level to a safe range. The researchers also suggest that optimizing the technical parameters of the procedure, such as the aspiration point and collection speed, can further enhance its efficiency.

Navigating the Complex World of Blood Disorders

This case report serves as a valuable reminder that managing blood disorders often requires a multidisciplinary approach and a careful consideration of the patient's individual needs. The researchers highlight the role of therapeutic thrombocytapheresis as a valuable tool in managing extreme thrombocytosis, complementing other treatments such as cytoreductive agents like hydroxyurea. As Dr. Camel always advises, "When navigating the complex world of blood disorders, it's essential to remember that there is no one-size-fits-all solution. A collaborative approach, involving the patient and a team of medical professionals, is essential to developing a personalized treatment plan that addresses the unique challenges of each case."

Dr.Camel's Conclusion

This case report offers a valuable glimpse into the clinical application of thrombocytapheresis in managing extreme thrombocytosis. It demonstrates the procedure's potential to improve the lives of patients facing this serious condition. The researchers' emphasis on the importance of optimizing the technical parameters of the procedure underscores the need for ongoing research and refinement in the field of blood disorder treatment. As Dr. Camel always says, "The world of blood disorders is vast and complex, much like a boundless desert. But with careful observation, innovative strategies, and a patient-centered approach, we can continue to develop new and effective treatments that provide hope to those facing these challenges."

Date :
  1. Date Completed 2020-01-15
  2. Date Revised 2020-01-15
Further Info :

Pubmed ID

30624802

DOI: Digital Object Identifier

10.1002/jca.21683

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English

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