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Anti-Diarrheal Drug Repositioning in Tumour Cell Cytotoxicity.
Author: AifaSami, Elloumi-MseddiJihene, FakhfakhRaouia, MsalbiDhouha
Original Abstract of the Article :
BACKGROUND: Drug repositioning is becoming an ideal strategy to select new anticancer drugs. In particular, drugs treating the side effects of chemotherapy are the best candidates. OBJECTIVE: In this present work, we undertook the evaluation of anti-tumour activity of two anti-diarrheal drugs (nifu...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/1871520619666190118120030
データ提供:米国国立医学図書館(NLM)
Repositioning Anti-diarrheal Drugs: A New Frontier in Cancer Treatment?
Drug repositioning, the practice of repurposing existing drugs for new indications, is gaining traction in the search for new cancer treatments. This study investigates the potential anti-tumor activity of two anti-diarrheal drugs, nifuroxazide and rifaximin. The researchers assessed the effects of these drugs on various breast cancer cell lines. They found that both nifuroxazide and rifaximin displayed cytotoxic effects, with nifuroxazide demonstrating a particularly strong late cytotoxicity effect against certain breast cancer cells. The study suggests that these anti-diarrheal drugs hold promise as potential dual-acting agents, capable of combating both cancer and the side effects of chemotherapy.
Anti-diarrheal Drugs: A Potential Double Whammy Against Cancer
This research opens the door to a new era in cancer treatment, potentially utilizing existing drugs with a dual-purpose - combating cancer while mitigating its side effects. The study's findings could lead to the development of novel and more effective cancer therapies.
A New Chapter in Cancer Treatment: Repurposing Drugs
The research highlights the exciting possibilities of drug repositioning in the field of cancer treatment. By repurposing existing drugs, researchers could potentially accelerate the development of new cancer therapies and enhance the lives of patients.
Dr. Camel's Conclusion
Just as a camel adapts to survive in a variety of environments, researchers are constantly exploring new ways to adapt existing drugs for new applications. This study highlights the potential of repurposing anti-diarrheal drugs for cancer treatment, offering a promising new avenue for research and development. This discovery could lead to more effective treatments and improved outcomes for patients battling cancer.
Date :
- Date Completed 2020-03-24
- Date Revised 2020-03-24
Further Info :
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English
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