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A 12-Week Maintenance Therapy with a New Prepared Viscous Budesonide in Pediatric Eosinophilic Esophagitis.
Author: CucchiaraSalvatore, IsoldiSara, MallardoSaverio, OlivaSalvatore, PapoffPaola, RossettiDanilo, RuggieroCosimo, RussoGiusy, TibertiAntonio, VezzoliDebora, VolpeDanila
Original Abstract of the Article :
BACKGROUND: A new prepared oral viscous budesonide (PVB) has been effective in inducing clinical and histological remission in pediatric eosinophilic esophagitis (EoE). AIMS: To evaluate the efficacy of a 12-week maintenance therapy on clinical, endoscopic, and histological remission using half of ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522447/
データ提供:米国国立医学図書館(NLM)
Maintenance Therapy with Viscous Budesonide for Pediatric Eosinophilic Esophagitis
This research explores the treatment of eosinophilic esophagitis (EoE), a chronic inflammatory condition affecting the esophagus, which is like navigating a sensitive and challenging desert terrain. The study focuses on the effectiveness of a new prepared oral viscous budesonide (PVB) for maintaining remission in children with EoE. The authors conducted a prospective study to evaluate the efficacy of a 12-week maintenance therapy using half the dose of PVB used in the induction phase. The study found that PVB effectively maintained remission at week 24, but the rate of relapse increased after the treatment was discontinued. This is like discovering a temporary oasis in the desert, offering relief from the discomfort of EoE, but requiring careful planning and management to avoid relapse.
Finding the Right Oasis: Maintaining Remission in EoE
The study highlights the importance of maintaining remission in EoE, a condition that can cause significant discomfort and complications. The researchers found that PVB effectively maintained remission at week 24, but the rate of relapse increased after the treatment was discontinued. This is like finding a temporary oasis in the desert, offering relief from the discomfort of EoE, but requiring careful planning and management to avoid relapse.
Managing EoE: Finding the Right Path
The study offers valuable insights into the long-term management of EoE. The researchers found that PVB is effective in maintaining remission, but further research is needed to explore strategies for reducing the rate of relapse. This is like finding a new path through the desert, a path that requires careful navigation and ongoing research to ensure the best possible outcomes for patients.
Dr.Camel's Conclusion
This research is a reminder that the desert of EoE treatment is vast and complex. The study offers valuable insights into the effectiveness of PVB for maintaining remission, but it also highlights the need for ongoing research to develop more effective long-term strategies for managing this challenging condition. It's a reminder that finding the right path through the desert requires both exploration and perseverance.
Date :
- Date Completed 2019-11-19
- Date Revised 2020-03-09
Further Info :
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