A 12-Week Maintenance Therapy with a New Prepared Viscous Budesonide in Pediatric Eosinophilic Esophagitis.

Author: CucchiaraSalvatore, IsoldiSara, MallardoSaverio, OlivaSalvatore, PapoffPaola, RossettiDanilo, RuggieroCosimo, RussoGiusy, TibertiAntonio, VezzoliDebora, VolpeDanila

Paper Details 
Original Abstract of the Article :
BACKGROUND: A new prepared oral viscous budesonide (PVB) has been effective in inducing clinical and histological remission in pediatric eosinophilic esophagitis (EoE). AIMS: To evaluate the efficacy of a 12-week maintenance therapy on clinical, endoscopic, and histological remission using half of ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522447/

データ提供:米国国立医学図書館(NLM)

Maintenance Therapy with Viscous Budesonide for Pediatric Eosinophilic Esophagitis

This research explores the treatment of eosinophilic esophagitis (EoE), a chronic inflammatory condition affecting the esophagus, which is like navigating a sensitive and challenging desert terrain. The study focuses on the effectiveness of a new prepared oral viscous budesonide (PVB) for maintaining remission in children with EoE. The authors conducted a prospective study to evaluate the efficacy of a 12-week maintenance therapy using half the dose of PVB used in the induction phase. The study found that PVB effectively maintained remission at week 24, but the rate of relapse increased after the treatment was discontinued. This is like discovering a temporary oasis in the desert, offering relief from the discomfort of EoE, but requiring careful planning and management to avoid relapse.

Finding the Right Oasis: Maintaining Remission in EoE

The study highlights the importance of maintaining remission in EoE, a condition that can cause significant discomfort and complications. The researchers found that PVB effectively maintained remission at week 24, but the rate of relapse increased after the treatment was discontinued. This is like finding a temporary oasis in the desert, offering relief from the discomfort of EoE, but requiring careful planning and management to avoid relapse.

Managing EoE: Finding the Right Path

The study offers valuable insights into the long-term management of EoE. The researchers found that PVB is effective in maintaining remission, but further research is needed to explore strategies for reducing the rate of relapse. This is like finding a new path through the desert, a path that requires careful navigation and ongoing research to ensure the best possible outcomes for patients.

Dr.Camel's Conclusion

This research is a reminder that the desert of EoE treatment is vast and complex. The study offers valuable insights into the effectiveness of PVB for maintaining remission, but it also highlights the need for ongoing research to develop more effective long-term strategies for managing this challenging condition. It's a reminder that finding the right path through the desert requires both exploration and perseverance.

Date :
  1. Date Completed 2019-11-19
  2. Date Revised 2020-03-09
Further Info :

Pubmed ID

30659470

DOI: Digital Object Identifier

PMC6522447

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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