Felodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.

Author: EllrodtA G, LangleyM S, MonkJ P, SaltielE

Paper Details 
Original Abstract of the Article :
Felodipine is a dihydropyridine calcium antagonist which selectively relaxes vascular smooth muscle. By acting at peripheral arterioles, it lowers systemic vascular resistance and thereby produces substantial decreases in blood pressure and increases in cardiac output. Felodipine is indicated for th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.2165/00003495-198836040-00002

データ提供:米国国立医学図書館(NLM)

Felodipine: A Desert Oasis for High Blood Pressure

Hypertension, a condition marked by high blood pressure, is a major public health concern, affecting millions worldwide. Imagine a desert landscape, where the wind relentlessly pushes against sand dunes, creating pressure and instability. Similarly, high blood pressure can exert undue pressure on blood vessels, potentially leading to serious health complications. This study explores the therapeutic potential of felodipine, a calcium channel blocker, in the management of hypertension, offering a potential oasis of relief for those struggling with this condition.

Felodipine: A Powerful Tool in Hypertension Management

The study demonstrates the efficacy of felodipine in lowering blood pressure, both as a monotherapy and as an adjunct to other antihypertensive medications. Imagine a camel navigating a treacherous desert, finding a sturdy rope to help it traverse challenging terrain. Similarly, felodipine can act as a vital lifeline for those with hypertension, helping to stabilize blood pressure and reduce the risk of serious complications. This research showcases the value of felodipine in hypertension management, offering a potential path towards improved cardiovascular health.

The Importance of Understanding Side Effects

The study also highlights the importance of considering the side effects of felodipine. Imagine a camel encountering a mirage in the desert, a deceptive image of water that ultimately leads to disappointment. Similarly, felodipine, while beneficial for blood pressure control, can also cause side effects, such as ankle swelling, headache, and flushing. It's crucial for healthcare providers to carefully weigh the risks and benefits of felodipine, ensuring its appropriate and safe use in individual patients. This study underscores the importance of a comprehensive understanding of both the benefits and potential drawbacks of medications like felodipine.

Dr. Camel's Conclusion

Felodipine offers a promising therapeutic option for hypertension, acting like a sturdy rope to help navigate the challenging terrain of high blood pressure. However, like a mirage in the desert, felodipine can have potential side effects that must be carefully considered. Through responsible use and careful monitoring, felodipine can be a valuable tool in the management of hypertension, promoting overall cardiovascular health and well-being.

Date :
  1. Date Completed 1989-05-02
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

3069435

DOI: Digital Object Identifier

10.2165/00003495-198836040-00002

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.