Systemic Retinoids and Scar Dehiscence.

Retinoids and Wound Healing: A Complex Relationship

Systemic retinoids, such as [isotretinoin and acitretin], are valuable for [treating various dermatological conditions]. However, these drugs are known for their potential [side effects], including [wound-healing complications]. This case report describes two patients who experienced [scar dehiscence] after initiating [systemic retinoid treatment] following [cutaneous surgery]. The authors suggest that [systemic retinoids] may [interfere with collagen production and fibroblast proliferation] during the [wound healing process], potentially leading to [scar dehiscence]. The authors recommend [postponing systemic retinoid treatment] for [6 months to 1 year] after [cutaneous surgery], particularly in [cosmetically important areas].

Retinoids and Wound Healing: A Balancing Act

The study highlights the importance of [considering the potential impact] of [systemic retinoid treatment] on [wound healing]. The authors suggest that [retinoic acid] may [interfere with the wound healing process] by [altering collagen production and fibroblast activity].

Timing is Key: Minimizing the Risk of Scar Dehiscence

The study's findings underscore the importance of [carefully coordinating] [systemic retinoid treatment] with [cutaneous surgery]. Postponing treatment for a [sufficient period] can help to [minimize the risk] of [scar dehiscence].

Dr.Camel's Conclusion

This case report highlights the need for [caution] when using [systemic retinoids] in patients who have undergone [cutaneous surgery]. The authors' recommendations for [postponing treatment] can help to [prevent scar dehiscence] and [improve wound healing outcomes]. It's like navigating a delicate ecosystem—a careful understanding of the interactions between [retinoids] and [wound healing] is crucial for achieving optimal results.