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Cilostazol may improve cognition better than clopidogrel in non-surgical adult patients with ischemic moyamoya disease: subanalysis of a prospective cohort.

Author: AndoSatoshi, ChibaTakayuki, FujiwaraShunrou, KobayashiMasakazu, KuboYoshitaka, MiyoshiKenya, OgasawaraKuniaki, SatoShinpei, SettaKengo, TsutsuiShouta, YanagiharaWataru, YoshidaKenji

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This study investigates the effects of clopidogrel and cilostazol, two antiplatelet drugs, on cognitive function in adult patients with ischemic moyamoya disease (MMD). While both drugs reportedly improve cognitive function over time, the study aims to determine which drug is more effective in non-surgical patients without severe hemodynamic compromise.
Paper Details　
Original Abstract of the Article :
Adult patients with ischemic moyamoya disease (MMD) who receive treatment with antiplatelet drugs reportedly show improvements in neuropsychological test scores after around 2 years. The purpose of the present study subanalyzing the same patient cohort used in a previous study was to determine which...See full text at original site
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引用元：
https://doi.org/10.1080/01616412.2019.1580455

データ提供：米国国立医学図書館（NLM）

Cilostazol vs. Clopidogrel in Ischemic Moyamoya Disease: A Cognitive Oasis in the Desert of Brain Disease

The [treatment of ischemic moyamoya disease (MMD)] is a challenging journey through a desert of cognitive impairment and vascular dysfunction. This study explores the potential cognitive benefits of [cilostazol] compared to [clopidogrel] in [non-surgical adult patients with ischemic MMD]. The researchers conducted a [sub-analysis of a prospective cohort] to compare the cognitive outcomes of patients receiving [cilostazol] to those receiving [clopidogrel]. The study's findings suggest that [cilostazol] may hold promise for improving cognitive function in this patient population.

Cilostazol: A Potential Cognitive Enhancer for Ischemic Moyamoya Disease

The study found that [cilostazol] was associated with [better cognitive function] compared to [clopidogrel] in [non-surgical adult patients with ischemic MMD]. This finding suggests that [cilostazol] may have [neuroprotective effects] that can benefit cognitive function in this challenging condition. Further research is needed to fully understand the mechanisms underlying these cognitive benefits.

Navigating the Desert of Cognitive Impairment

The study's findings highlight the importance of [considering the cognitive impact] of different treatment options for [MMD]. By optimizing treatment strategies and exploring [neuroprotective agents] like [cilostazol], we can potentially improve cognitive function and quality of life for individuals living with this debilitating condition.

Dr.Camel's Conclusion

As a researcher who has spent years studying the intricate workings of the brain, I am always fascinated by the search for treatments that can protect and enhance cognitive function. This study offers a glimpse into the potential of [cilostazol] to improve cognitive outcomes for [MMD patients]. Continued research is essential to unlock the full potential of this promising agent and improve the lives of those living with this challenging condition.
Date :
  1. Date Completed 2019-04-18
  2. Date Revised 2019-04-18
Further Info :

Pubmed ID

30774013

DOI: Digital Object Identifier

10.1080/01616412.2019.1580455

Related Literature

Article Analysis
・Side Effects of cilostazol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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