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Investigation of dacomitinib on reducing cell necrosis and enhancing cell apoptosis in C6 glioma rat model by MRI.

Author: ChenWang-Sheng, HongLan, LiJian-Jun, WangFei

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Dacomitinib, a drug that inhibits the epidermal growth factor receptor (EGFR), has shown promise in treating glioma, a type of brain cancer. This study investigates the regional effects of Dacomitinib on tumor necrosis.
Paper Details　
Original Abstract of the Article :
Label="BACKGROUND">Glioma is one of the most epidemic and obstinate types of cancer in the central nervous system (CNS) with poor survival rate. Dacomitinib inhibited cell viability and proliferation of&#160;epidermal growth factor receptor (<i>EGFR</i>)-amplified glioma. In the present study, the r...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400661/

データ提供：米国国立医学図書館（NLM）

Targeting Glioma with Dacomitinib: A New Approach

Glioma, a type of brain tumor, is like a treacherous sandstorm, difficult to control and often leading to devastating consequences. This study focuses on dacomitinib, a potential weapon against glioma, and its impact on tumor necrosis.

Dacomitinib Shows Promise in Reducing Glioma Necrosis

The research team used an animal model to investigate the effects of dacomitinib on glioma. Their findings suggest that dacomitinib may be effective in reducing tumor necrosis, an important step in the fight against glioma. This discovery represents a potential oasis in the desert of glioma treatment.

Hope for Glioma Patients: A New Tool in the Fight

While further research is needed, this study provides promising evidence for dacomitinib's potential to improve the lives of glioma patients. This research serves as a beacon of hope in the difficult journey against this challenging disease.

Dr.Camel's Conclusion

This research is a ray of sunshine in the vast and often unforgiving desert of brain cancer research. The potential of dacomitinib in reducing tumor necrosis offers a glimmer of hope for patients battling this aggressive disease. While the journey towards a cure is long, this study reinforces the importance of relentless exploration in the quest to conquer glioma.

Date :
  1. Date Completed 2020-02-20
  2. Date Revised 2020-03-09
Further Info :

Pubmed ID

30782784

DOI: Digital Object Identifier

PMC6400661

Related Literature

Article Analysis
・Effects of dacomitinib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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