Effectiveness of intravenous dexamethasone, metoclopramide, ketorolac, and chlorpromazine for pain relief and prevention of recurrence in the migraine headache: a prospective double-blind randomized clinical trial.

Author: Ghafouri-FardSoudeh, Hosseini Nejad MirNahid, KhazaeiMojtaba, TaheriMohammad, Yadranji AghdamFateme

Paper Details 
Original Abstract of the Article :
Dexamethasone, metoclopramide, ketorolac, and chlorpromazine have been used for the treatment of migraine headache. However, the effectiveness of these drugs in pain relief and prevention of recurrence and their side effects have not been compared yet. This was a randomized, double-blind clinical tr...See full text at original site
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引用元:
https://doi.org/10.1007/s10072-019-03766-x

データ提供:米国国立医学図書館(NLM)

A Desert of Migraine Relief: Searching for the Oasis

The constant pain of a migraine headache is like a scorching desert sun beating down on you. This study ventures into this desert to search for relief, investigating the effectiveness of intravenous dexamethasone, metoclopramide, ketorolac, and chlorpromazine in treating acute migraine attacks. The study is a randomized, double-blind clinical trial involving patients who received one of these drugs intravenously. The results show that all four drugs provided statistically significant relief from migraine pain, but dexamethasone demonstrated a trend toward greater effectiveness in preventing recurrence. The study also revealed that dexamethasone was associated with fewer side effects compared to chlorpromazine.

Dexamethasone: A Potential Oasis in the Migraine Desert

The study's findings suggest that dexamethasone might be a promising option for preventing migraine recurrence. The trend towards greater effectiveness in preventing recurrence, coupled with its lower side effect profile, make dexamethasone a potentially valuable tool in the fight against migraine headaches. The study's findings are encouraging and provide a glimmer of hope in the desert of migraine pain.

Navigating the Migraine Desert: Staying Hydrated and Prepared

Living with migraine headaches can be a challenging journey. This research emphasizes the importance of finding the right treatment strategy for individual patients. It is crucial to work with a healthcare professional to identify the best course of action and address any concerns or potential side effects. Taking steps to manage triggers, staying hydrated, and ensuring adequate sleep can also help to prevent or reduce the frequency and severity of migraine attacks.

Dr.Camel's Conclusion

The search for migraine relief is a continuous journey through a desert of pain. This study provides valuable insights into the potential benefits of dexamethasone as a treatment option. It is a reminder that finding the right path through this desert often requires a collaborative effort between patients and healthcare providers. By working together, we can navigate the challenges of migraine headaches and find a path to relief.

Date :
  1. Date Completed 2019-06-10
  2. Date Revised 2022-11-17
Further Info :

Pubmed ID

30783794

DOI: Digital Object Identifier

10.1007/s10072-019-03766-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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