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Pretreatment Neutrophil to Lymphocyte Ratio (NLR) Predicts Prognosis for Castration Resistant Prostate Cancer Patients Underwent Enzalutamide.
Author: HasegawaYoriko, KawaharaTakashi, KumanoYohei, MatsubaraNobuaki, MiyoshiYasuhide, UemuraHiroji, YasuiMasato
Original Abstract of the Article :
Nearly 80% of advanced prostate cancer patients respond to initial androgen deprivation therapy (ADT). However, ADT does not prevent the progression of prostate cancer over the long term, and the disease eventually progresses to castration-resistant prostate cancer (CRPC). Prior to the development o...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360569/
データ提供:米国国立医学図書館(NLM)
Castration-Resistant Prostate Cancer: A Desert of Treatment Challenges
Prostate cancer, like a slow-moving sandstorm, can pose significant challenges for patients. This study, like a research team exploring the desert of prostate cancer treatment, investigates the role of the neutrophil-to-lymphocyte ratio (NLR) as a predictive biomarker for the effectiveness of enzalutamide (ENZ), a medication used to treat castration-resistant prostate cancer (CRPC). The authors seek to identify potential predictors of treatment response, hoping to guide clinicians toward more effective and personalized treatment strategies.
A Desert Oasis: Finding a Predictive Tool
The study, like a traveler seeking a water source in the desert, explores the potential of NLR as a predictor of prognosis for CRPC patients undergoing ENZ treatment. The authors meticulously analyze the data, hoping to identify a valuable tool that can help clinicians anticipate treatment response and personalize treatment plans based on individual patient characteristics. The findings suggest that NLR might hold promise as a readily available and cost-effective biomarker for predicting ENZ efficacy in CRPC patients, potentially informing treatment decisions and optimizing patient outcomes.
A Path to Personalized Care: Navigating the Desert with Precision
This study, like a compass guiding travelers through the desert, highlights the importance of personalized care in managing CRPC. The authors underscore the need for ongoing research to validate the role of NLR as a predictive biomarker, aiming to refine treatment strategies and improve outcomes for patients with this challenging condition. By embracing a data-driven approach and leveraging insights from research, clinicians can potentially enhance patient care and navigate the complexities of CRPC treatment with greater precision.
Dr.Camel's Conclusion
This research provides a valuable contribution to the field of prostate cancer management, exploring the potential of NLR as a predictive biomarker for the effectiveness of enzalutamide in treating castration-resistant prostate cancer. The findings highlight the importance of personalized care and the need for ongoing research to refine treatment strategies. By embracing a data-driven approach and leveraging insights from research, healthcare professionals can potentially improve patient outcomes and navigate the challenges of prostate cancer treatment with greater precision.
Date :
- Date Completed 2019-06-10
- Date Revised 2022-03-31
Further Info :
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