Paper Details 
Original Abstract of the Article :
This chapter covers antidepressants that fall into the class of serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors. That is, they bind to the 5-HT and NE transporters with varying levels of potency and binding affinity ratios. Unlike the selective serotonin (5-HT) reuptake inhibitors (SSRI...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/164_2018_164

データ提供:米国国立医学図書館(NLM)

Serotonin and Norepinephrine Reuptake Inhibitors: A Comprehensive Review

This chapter delves into the world of antidepressants, specifically those belonging to the class of serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors. These medications exert their effects by binding to the 5-HT and NE transporters, influencing the levels of these neurotransmitters in the brain. The chapter offers a comprehensive review of the chemistry, pharmacology, metabolism, safety, and clinical applications of each antidepressant within this class.

A Spectrum of Antidepressants

The chapter provides a detailed analysis of different serotonin and norepinephrine reuptake inhibitors, highlighting their unique pharmacological profiles and clinical applications. The researchers emphasize the importance of understanding the dose-response curves of these medications, as they can vary significantly based on the specific drug and the individual patient. The chapter also addresses potential drug interactions and adverse effects associated with these medications, providing valuable insights for clinicians and patients.

Implications for Mental Health Treatment

This chapter offers a comprehensive overview of the serotonin and norepinephrine reuptake inhibitors, providing essential information for clinicians and patients seeking effective treatment for depression and other mental health conditions. The researchers' insights into the pharmacological properties, clinical applications, and safety profiles of these medications are invaluable for making informed decisions about treatment options.

Dr. Camel's Conclusion

Think of these antidepressants as a skilled desert guide, navigating the often-turbulent landscape of the mind. This chapter provides a detailed roadmap, helping us understand the different approaches and nuances of these medications, allowing for a more personalized and effective treatment journey.

Date :
  1. Date Completed 2019-07-22
  2. Date Revised 2019-07-22
Further Info :

Pubmed ID

30838456

DOI: Digital Object Identifier

10.1007/164_2018_164

SNS
PICO Info
in preparation
Languages

English

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