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Isolation of group B Streptococcus with reduced β-lactam susceptibility from pregnant women.
Author: ArakawaYoshichika, BannoHirotsugu, JinWanchun, KikkawaFumitaka, KimuraKouji, KotaniTomomi, MitsuiTakashi, MoroiHiroaki, TsudaHiroyuki, WachinoJun-Ichi, YamadaKeiko, YamashitaMamoru
Original Abstract of the Article :
β-Lactam antibiotics are first-line agents for the treatment and prevention of group B Streptococcus (GBS) infections. We previously reported clinical GBS isolates with reduced β-lactam susceptibility (GBS-RBS) and characterized them as harbouring amino acid substitutions in penicillin-binding prote...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455180/
データ提供:米国国立医学図書館(NLM)
Group B Streptococcus: Navigating the Shifting Sands of Antimicrobial Resistance
Antimicrobial resistance, a growing concern in healthcare, poses a significant threat to public health. This study, like a vigilant camel scout monitoring the desert landscape for signs of change, investigates the emergence of group B Streptococcus (GBS) isolates with reduced susceptibility to β-lactam antibiotics. The authors meticulously characterized these isolates from pregnant women, aiming to understand the mechanisms behind this resistance.
A New Threat: The Emergence of β-Lactam-Resistant GBS
This research reveals the emergence of GBS isolates with reduced susceptibility to β-lactam antibiotics, a concerning development in the fight against bacterial infections. The authors identified amino acid substitutions in penicillin-binding proteins (PBPs) as a primary mechanism behind this resistance.
Protecting Mothers and Babies: Addressing Antibiotic Resistance
Antibiotic resistance is a complex challenge that requires a multifaceted approach. Maintaining a vigilant surveillance for resistant strains, implementing appropriate infection control measures, and promoting responsible antibiotic use are essential for protecting both mothers and babies from the threat of resistant GBS infections.
Dr.Camel's Conclusion
This study underscores the importance of ongoing surveillance and research in addressing the challenge of antimicrobial resistance. Just as a wise camel guide must be aware of the changing desert landscape, healthcare professionals must be vigilant in monitoring the emergence of drug-resistant bacteria. By understanding the mechanisms behind resistance and adopting responsible antibiotic use practices, we can strive to preserve the effectiveness of these essential medications.
Date :
- Date Completed 2019-07-01
- Date Revised 2020-02-25
Further Info :
Related Literature
English
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