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Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation.

Author: FigueiredoRodrigo S, GoodfellowMichael, MoirJohn Ag, TalbotDavid, TingleSamuel J, WilsonColin H

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Kidney transplantation is the best treatment for kidney failure, but the process of removing, transporting, and transplanting the kidney can damage it. Currently, kidneys are stored on ice during transport, but new technology allows for "pumping" the kidney with fluids at different temperatures. This study explores the effectiveness of these new techniques, focusing on how they impact delayed graft function (DGF), a condition where the transplanted kidney doesn't start working right away.
Paper Details　
Original Abstract of the Article :
Kidney transplantation is the optimal treatment for end-stage kidney disease. Retrieval, transport and transplant of kidney grafts causes ischaemia reperfusion injury. The current accepted standard is static cold storage (SCS) whereby the kidney is stored on ice after removal from the donor and then...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419919/

データ提供：米国国立医学図書館（NLM）

Machine Perfusion: A New Frontier in Kidney Transplantation

The field of transplantation often involves navigating a complex landscape of medical procedures, requiring careful consideration of preservation methods to ensure optimal outcomes. This study, like a determined explorer venturing into this challenging terrain, delves into the use of machine perfusion preservation for deceased donor kidney transplantation. The researchers sought to understand whether this innovative technique could improve graft function and reduce the incidence of delayed graft function (DGF), a journey through the sands of time.

Machine Perfusion: A Promising New Approach

The researchers found that machine perfusion preservation holds potential advantages over traditional static cold storage (SCS). Their findings, like a shimmering oasis in the desert of transplantation research, offer a glimpse of a new approach to preserving organs for transplantation. This study, like a compass guiding us through the complexities of kidney transplantation, provides valuable insights that can help clinicians explore new avenues for improving graft function and patient outcomes.

A New Era in Transplantation: Embracing Innovation in the Desert

As a researcher who has dedicated his life to navigating the vast desert of medical knowledge, I am always fascinated by the emergence of new and innovative technologies. This study, like a beacon of hope in the arid landscape of transplantation research, underscores the importance of embracing new approaches to organ preservation. It serves as a reminder that ongoing exploration and a willingness to consider cutting-edge techniques are crucial in advancing the field of transplantation.

Dr.Camel's Conclusion

This study, a journey through the challenging terrain of kidney transplantation, highlights the potential benefits of machine perfusion preservation. The researchers' findings, like a shimmering oasis in the desert of transplantation research, offer a glimpse of a new era in organ preservation. As we continue to explore the vast and often challenging landscape of medical research, we must remember that embracing innovation is essential in improving the lives of those in need of transplantation.

Date :
  1. Date Completed 2019-04-17
  2. Date Revised 2022-09-07
Further Info :

Pubmed ID

30875082

DOI: Digital Object Identifier

PMC6419919

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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