Optimal treatment of opioid induced constipation in daily clinical practice - an observational study.

Author: BeekerAart, BerkhofJohannes, NeefjesElisabeth C W, RhodiusChristiaan A, Ten OeverDiederik, VerheulHenk M W, van den BergHendrik P, van der VlietHans J, van der VorstMaurice J D L, van der WijngaartHanneke

Paper Details 
Original Abstract of the Article :
Opioids are prescribed in over 40% of patients with advanced cancer, but side effects occur frequently. In this study we evaluated the development and treatment of opioid induced constipation (OIC), and OIC resolving effect of methylnaltrexone for different opioid subtypes in daily clinical practice...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439982/

データ提供:米国国立医学図書館(NLM)

Opioid-Induced Constipation: A Common Side Effect

Opioids, a class of medications commonly used to manage pain, can cause a debilitating side effect: opioid-induced constipation (OIC). This study explores the prevalence and treatment of OIC in patients with advanced cancer, a population that frequently relies on opioid therapy. The authors, like skilled physicians navigating the complexities of pain management, investigated the patterns and effectiveness of treatments for OIC in this patient population.

Navigating the Desert of Constipation

The study found that OIC is a common and often challenging problem for patients receiving opioids. This is like a caravan encountering a sandstorm, where the journey becomes arduous and progress is hindered. The researchers, like explorers searching for a solution to a desert drought, evaluated the efficacy of methylnaltrexone, a medication specifically designed to relieve OIC. The study found that methylnaltrexone was effective in resolving OIC, offering relief for patients struggling with this uncomfortable side effect. This is like discovering a new oasis, providing a source of relief and hydration in a parched landscape.

A New Oasis for Opioid Management

The study's findings highlight the importance of proactive management of OIC in patients receiving opioids. This is like preparing for a desert journey, packing the necessary supplies and making sure the caravan is equipped to handle any challenges. The authors emphasize the need for early intervention and a personalized approach to OIC, selecting the most appropriate treatment option for each patient. This is like adapting to the changing environment of the desert, choosing the right path and tools to navigate the terrain safely and effectively.

Dr.Camel's Conclusion

This study underscores the importance of addressing OIC, a common and often debilitating side effect of opioid therapy. Methylnaltrexone offers a valuable tool for managing this condition, providing relief for patients and enhancing their overall well-being. Like a caravan navigating a challenging desert landscape, we must be prepared to address the unique challenges of opioid management and ensure the comfort and safety of our patients.

Date :
  1. Date Completed 2019-09-24
  2. Date Revised 2020-02-25
Further Info :

Pubmed ID

30922276

DOI: Digital Object Identifier

PMC6439982

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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