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Efficacy and safety of erythropoietin and iron therapy to reduce red blood cell transfusion in surgical patients: a systematic review and meta-analysis.

Author: CurleyGerard, GauthierMarie-France, HareGregory M T, KeiTiffanie, MazerC David, MistryNikhil, PavenskiKaterina, SchweizerTom A, ShehataNadine, TanziniRosa Maria, ThorpeKevin, WardSarah

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

This study compares the efficacy and safety of erythropoiesis stimulating agents (ESAs) and iron therapy versus iron therapy alone in reducing red blood cell (RBC) transfusion for surgical patients with iron restricted anemia.
Paper Details　
Original Abstract of the Article :
Iron restricted anemia is prevalent in surgical patients and is associated with an increased risk of allogeneic red blood cell (RBC) transfusion and adverse events. Treatment of anemia includes oral and intravenous iron and erythropoiesis stimulating agents (ESAs). More recent studies have focused o...See full text at original site
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引用元：
https://doi.org/10.1007/s12630-019-01351-6

データ提供：米国国立医学図書館（NLM）

Erythropoietin and Iron Therapy: A Lifeline for Anemic Surgical Patients

Iron-restricted anemia is a common problem in surgical patients, increasing the risk of blood transfusions and adverse outcomes. This research, published in [Journal Name], delves into the efficacy and safety of erythropoietin and iron therapy in reducing the need for blood transfusions in surgical patients. The researchers conducted a systematic review and meta-analysis of studies evaluating different treatment strategies, including iron therapy alone and combined erythropoietin and iron therapy. Their findings suggest that combined erythropoietin and iron therapy is more effective than iron therapy alone in reducing blood transfusion requirements in surgical patients. This approach offers a potential solution to the challenges posed by anemia in this patient population.

Erythropoietin and Iron: A Powerful Partnership

This research, published in [Journal Name], highlights the potential benefits of combining erythropoietin and iron therapy in treating surgical patients with iron-restricted anemia. The results suggest that this approach can significantly reduce the need for blood transfusions, leading to improved patient outcomes.

Boosting Blood: A Desert Oasis for Anemia

Anemia can be as draining as crossing a vast desert, leaving individuals feeling weak and tired. This research, published in [Journal Name], offers a potential oasis for surgical patients by demonstrating the effectiveness of combined erythropoietin and iron therapy in managing anemia and reducing the need for blood transfusions.

Dr.Camel's Conclusion

Just as a camel relies on its stores of water and nutrients to survive the desert, surgical patients with anemia need support to recover. This research underscores the value of combining erythropoietin and iron therapy, offering a potential lifeline for anemic patients in the surgical desert.

Date :
  1. Date Completed 2020-10-01
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

30924000

DOI: Digital Object Identifier

10.1007/s12630-019-01351-6

Related Literature

Article Analysis
・Effective treatment of anemia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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