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Umbralisib: Treatment for a Rare Lymphoma?

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Overview

Umbralisib, a PI3Kδ inhibitor, showed promising results in a phase IIb trial for patients with relapsed/refractory marginal zone lymphoma. It achieved a 55% response rate and a 71% 1-year progression-free survival rate, with manageable side effects.
Paper Details　
Original Abstract of the Article :
The PI3Kδ inhibitor umbralisib may be a promising therapy for patients with relapsed/refractory marginal zone lymphoma: In the phase IIb UNITY-NHL tr...See full text at original site
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引用元：
https://doi.org/10.1158/2159-8290.CD-NB2019-045

データ提供：米国国立医学図書館（NLM）

Umbralisib: A New Hope for a Rare Lymphoma?

[Marginal zone lymphoma (MZL)] is a [rare type of lymphoma] that can be challenging to treat. This study explores the [potential of umbralisib], a [PI3Kδ inhibitor], as a [treatment option] for [relapsed/refractory MZL]. The authors [conducted a phase IIb clinical trial] to evaluate the [efficacy and safety] of [umbralisib]. Their findings [suggest] that [umbralisib] may be a [promising treatment option] for [patients with MZL].

A New Oasis in the Lymphoma Desert: The Potential of Umbralisib

Imagine [MZL] as [a vast and unforgiving desert] where [treatment options] are [limited] and [survival rates] are [low]. This study [identifies a potential oasis] in the [desert of MZL] – [umbralisib]. The researchers [conducted a clinical trial] to [evaluate the effectiveness] and [safety] of [umbralisib] in [treating MZL].

A New Path to Recovery: Exploring Umbralisib for Marginal Zone Lymphoma

This research [sheds light] on the [potential of umbralisib] as a [treatment option] for [MZL]. The study [suggests] that [umbralisib] may [improve response rates] and [prolong survival] for [patients with MZL].

Dr.Camel's Conclusion

This study [offers a glimmer of hope] for [patients with MZL]. It [highlights the importance] of [continued research] to [develop new treatments] for [rare cancers] and [improve patient outcomes].

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-02-26
Further Info :

Pubmed ID

30936084

DOI: Digital Object Identifier

10.1158/2159-8290.CD-NB2019-045

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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