Paper Details 
Original Abstract of the Article :
BACKGROUND: Direct-acting antivirals (DAAs), including sofosbuvir (SOF), are recommended for treatment of chronic hepatitis C virus (HCV) infection. However, few studies have investigated the effectiveness and safety of new DAAs in kidney transplant recipients (KTRs). OBJECTIVES: To assess the effe...See full text at original site
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引用元:
https://doi.org/10.1111/tid.13090

データ提供:米国国立医学図書館(NLM)

Hepatitis C: A New Era of Treatment for Kidney Transplant Recipients

Chronic hepatitis C virus (HCV) infection is a major health concern, and kidney transplant recipients (KTRs) are particularly vulnerable to complications. This study investigates the effectiveness and safety of sofosbuvir-based therapy in treating HCV infection in stable KTRs. Imagine a desert where HCV parasites threaten the delicate balance of a transplanted kidney, putting a patient's health at risk.

The researchers found that sofosbuvir-based therapies were highly effective in achieving sustained virologic response in KTRs. However, the study also highlighted the importance of monitoring blood hemoglobin levels, as sofosbuvir-based therapy can lead to a decrease in hemoglobin. It's like finding a powerful oasis in the desert, but needing to carefully monitor the water levels to avoid dehydration.

New Hope for HCV Infection in Transplant Patients

This study provides promising evidence for the effectiveness of sofosbuvir-based therapy in treating HCV infection in KTRs. These therapies offer a new era of treatment for this challenging condition in a vulnerable patient population. It's like discovering a new source of water in a desert, bringing hope and a chance for a healthier future.

Important Considerations for Treatment

The study also emphasizes the need for close monitoring of blood hemoglobin levels during sofosbuvir-based therapy. Adjusting the dose of ribavirin, a common co-treatment, may be necessary to prevent anemia. It's like having a skilled guide in the desert, ensuring the travelers have the right supplies and adjustments are made when needed.

Dr.Camel's Conclusion

This study demonstrates the potential of sofosbuvir-based therapies in improving the lives of kidney transplant recipients with chronic HCV infection. It's a reminder that we need to keep exploring new treatment options and carefully monitor patients to ensure their well-being. It's like embarking on a journey through a vast desert, where continuous vigilance and careful planning are essential for reaching the oasis of health.

Date :
  1. Date Completed 2019-08-02
  2. Date Revised 2019-08-02
Further Info :

Pubmed ID

30972854

DOI: Digital Object Identifier

10.1111/tid.13090

Related Literature

SNS
PICO Info
in preparation
Languages

English

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