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Oxidative Effects of Gemifloxacin on Some Biological Traits of Drosophila melanogaster (Diptera: Drosophilidae).

Author: AslanNilay, BüyükgüzelEnder, BüyükgüzelKemal

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effects of gemifloxacin, a DNA gyrase and topoisomerases inhibitor, on Drosophila melanogaster (Meigen). The study found that sublethal doses of gemifloxacin significantly impaired adult fitness and life-history parameters in D. melanogaster, likely due to its oxidative effects.
Paper Details　
Original Abstract of the Article :
In recent times, several studies have been undertaken on the artificial mass-rearing of insects in which clinical antibacterial antibiotics, including gemifloxacin, which is a DNA gyrase and topoisomerases inhibitor, are amended into the diet to control microbial contamination and preserve diet. The...See full text at original site
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引用元：
https://doi.org/10.1093/ee/nvz039

データ提供：米国国立医学図書館（NLM）

The Oxidative Effects of Gemifloxacin on Drosophila melanogaster: A Cautionary Tale

This research investigates the potential impact of gemifloxacin, a commonly used antibiotic, on the biological traits of Drosophila melanogaster, a fruit fly often used in scientific studies. The study explores the effects of gemifloxacin on the flies' survival, development, and longevity.

The researchers exposed fruit flies to different doses of gemifloxacin during their development. They measured the effects on the flies' survival rates, development times, and lifespan. They also investigated the oxidative effects of gemifloxacin on the flies' eggs.

Gemifloxacin: A Potential Threat to Insect Health?

The study revealed that gemifloxacin, even at sublethal doses, had a significant impact on the flies' biological traits, causing a decrease in survival, delayed development, and reduced lifespan. These findings suggest that gemifloxacin may have detrimental effects on insect health.

Beyond the Lab: Environmental Considerations

This research highlights the importance of considering the potential environmental impact of antibiotics. Just as the desert ecosystem is delicately balanced, the use of antibiotics can have unintended consequences on non-target organisms.

Dr.Camel's Conclusion

This study serves as a cautionary tale about the potential effects of antibiotics on non-target organisms. While gemifloxacin is a valuable tool in treating bacterial infections, its widespread use could have unintended consequences for insect populations.

Date :
  1. Date Completed 2019-10-16
  2. Date Revised 2019-10-16
Further Info :

Pubmed ID

30994172

DOI: Digital Object Identifier

10.1093/ee/nvz039

Related Literature

Article Analysis
・Effects of gemifloxacin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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