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Plant Extracts Display Synergism with Different Classes of Antibiotics.

Author: CostaPriscilla A DA, DiazMarisa A N, GasparDiaz-Muñoz, PurgatoGislaine A, RibonAndréa O B, SilvaDanielle M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Plant extracts combined with antibiotics demonstrated synergistic antimicrobial activity against Staphylococcus aureus. The combination of Plectranthus ornatus extract with ampicillin, kanamycin, and gentamicin resulted in 8-fold reductions in the minimum inhibitory concentrations (MICs) of the antibiotics. These findings suggest that combining plant extracts with antibiotics could reduce the required doses, potentially mitigating side effects and treatment costs.
Paper Details　
Original Abstract of the Article :
One manner in which plant-derived compounds exert their antibiotic potential is the synergism, a positive interaction between two compounds. Studies indicate that the use of plant extracts combined with antimicrobials may promote a significant reduction of the minimum inhibitory concentrations of an...See full text at original site
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引用元：
https://doi.org/10.1590/0001-3765201920180117

データ提供：米国国立医学図書館（NLM）

Synergistic Effects of Plant Extracts and Antibiotics against Staphylococcus aureus

Staphylococcus aureus is a common bacterial pathogen that can cause a range of infections. This study explores the potential of plant extracts as natural antimicrobial agents, specifically investigating their synergistic effects with different classes of antibiotics against S. aureus. The study aimed to evaluate the antimicrobial activity of plant extracts and their combinations with antibiotics, seeking to enhance the effectiveness of antibiotic treatments.

The Power of Plant-Based Synergism

The research identified several plant extracts that demonstrated synergistic effects with antibiotics, significantly reducing the minimum inhibitory concentrations (MICs) of antibiotics for S. aureus. These findings suggest that combining plant extracts with antibiotics could enhance their effectiveness and potentially reduce the dosage required for treatment, potentially minimizing side effects.

Harnessing Nature's Power for Treatment

This research highlights the potential of harnessing nature's bounty for new therapeutic approaches. The synergistic effects of plant extracts with antibiotics offer a promising avenue for developing more effective and safer antimicrobial treatments. It's like discovering a hidden treasure trove of natural remedies in the vast desert of medicinal plants.

Dr.Camel's Conclusion

This study underscores the potential of combining plant extracts with antibiotics to enhance their effectiveness against bacterial infections. It's a testament to the power of nature and the ongoing search for new therapeutic solutions. Like a skilled desert traveler, researchers are exploring the vast landscape of natural remedies, seeking to uncover new treasures to improve human health.

Date :
  1. Date Completed 2019-06-06
  2. Date Revised 2019-06-06
Further Info :

Pubmed ID

31090789

DOI: Digital Object Identifier

10.1590/0001-3765201920180117

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English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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