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CVT-301 for the treatment of Parkinson's disease.

Author: BetteSagari, Di LucaDaniel G, MargoleskyJason, ShpinerDanielle S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study reviews the available treatments for motor and nonmotor fluctuations in Parkinson's disease (PD), including medications and surgical procedures. The review focuses on CVT-301 (Inbrija), an inhaled formulation of levodopa (LD), which provides a safe and effective delivery mechanism for rescue therapy in PD patients.
Paper Details　
Original Abstract of the Article :
<b>Introduction</b>: For patients with Parkinson's disease (PD), the treatment of motor and nonmotor fluctuations is tantamount to maintaining quality of life. Subcutaneous apomorphine has been the only commercially available rescue therapy for the treatment of OFF episodes. In December 2018, CVT-3...See full text at original site
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引用元：
https://doi.org/10.1080/14737175.2019.1621748

データ提供：米国国立医学図書館（NLM）

Inhaled Levodopa (CVT-301): A New Hope for Parkinson's Disease Management

Parkinson's disease (PD) is a chronic neurodegenerative disorder that affects millions of people worldwide. Managing motor fluctuations, including "OFF" episodes, is a significant challenge for PD patients, impacting their quality of life. This review discusses the development of CVT-301 (Inbrija), an inhaled formulation of levodopa, as a new treatment option for managing motor fluctuations in PD. The review explores the pharmacological properties, efficacy, and safety of CVT-301, comparing it to existing treatment options, including subcutaneous apomorphine and deep brain stimulation (DBS).

CVT-301: A Novel Approach to Managing Motor Fluctuations in PD

The review highlights the potential of CVT-301 as a safe and effective treatment option for managing motor fluctuations in PD. The inhaled formulation offers a convenient and potentially preferable alternative to subcutaneous injections, providing rapid and durable symptom relief for patients experiencing "OFF" episodes. This research opens new doors for improving the management of PD, offering patients a more comfortable and accessible treatment option.

Navigating Parkinson's Disease: A Search for Effective Solutions

This review emphasizes the ongoing search for effective treatments for PD, particularly for managing motor fluctuations. The development of CVT-301 represents a significant step forward in this endeavor, offering a novel and potentially superior alternative to existing treatment options. This research underscores the importance of continued innovation and exploration in the field of PD treatment, aiming to improve the quality of life for individuals living with this challenging condition.

Dr.Camel's Conclusion

This review highlights the potential of CVT-301 (Inbrija) as a safe and effective treatment option for managing motor fluctuations in PD. The inhaled formulation offers a convenient and potentially preferable alternative to subcutaneous injections, providing rapid and durable symptom relief. This research signifies a significant advancement in the field of PD treatment, offering a new avenue for improving the quality of life for individuals living with this condition.

Date :
  1. Date Completed 2020-08-20
  2. Date Revised 2020-08-20
Further Info :

Pubmed ID

31104518

DOI: Digital Object Identifier

10.1080/14737175.2019.1621748

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in preparation
Languages

English

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