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Medroxyprogesterone Acetate in Gender-Affirming Therapy for Transwomen: Results From a Retrospective Study.
Author: ForcierMichelle, JainJaison, KwanDaniel
Original Abstract of the Article :
CONTEXT: Medroxyprogesterone acetate (MPA) is a widely used progestin in feminizing hormone therapy. However, the side effects and hormonal changes elicited by this drug have never been investigated in the transgender population. OBJECTIVE: We evaluated the incidence of self-reported effects among ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1210/jc.2018-02253
データ提供:米国国立医学図書館(NLM)
The Role of Medroxyprogesterone Acetate in Gender-Affirming Therapy
The field of gender-affirming therapy is constantly evolving, and researchers are always seeking new ways to improve the lives of transgender individuals. This particular study delves into the use of Medroxyprogesterone Acetate (MPA) in feminizing hormone therapy for transwomen. It's like exploring a vast desert, searching for the right oasis of hormones to bring about a sense of well-being. The researchers used a retrospective approach, examining data from 290 follow-up visits of transwomen treated at Rhode Island Hospital. The study focused on comparing the effects of MPA treatment with those who didn't receive it.
MPA's Effect on Hormones and Side Effects
The study discovered that MPA was associated with a decrease in testosterone levels while maintaining relatively stable estradiol levels. This is a significant finding, as it suggests that MPA can contribute to feminization without disrupting the delicate balance of hormones. Imagine it as a steady, gentle wind guiding a camel through the desert, leading it towards its destination. The study also reported minimal side effects, with only a small number of patients experiencing mood swings. This is encouraging news, as it suggests that MPA is generally well-tolerated by transwomen.
The Importance of Future Research
The findings of this study are promising, but it's crucial to remember that further research is needed to confirm these results. Prospective studies with larger sample sizes and more comprehensive assessments will be essential to provide a more robust understanding of MPA's long-term effects. Think of it like planting a seed in the desert – we need to nurture it with more research to see it grow into a full-fledged understanding of the therapeutic potential of MPA.
Dr.Camel's Conclusion
This study offers a glimpse into the potential benefits of MPA in gender-affirming therapy for transwomen. However, it's crucial to remember that this is just one piece of the puzzle. As a wise camel, I urge you to approach this information with a discerning mind, recognizing the need for further research before making definitive conclusions. More research will help us create a brighter future for transgender individuals, a future where everyone can feel comfortable and confident in their own skin.
Date :
- Date Completed 2020-06-01
- Date Revised 2020-06-01
Further Info :
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