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Dienogest or Norethindrone acetate for the treatment of ovarian endometriomas: Can we avoid surgery?

Author: ArenaAlessandro, Del FornoSimona, GiaquintoIlaria, MabroukMohamed, MattioliGiulia, ParadisiRoberto, SeracchioliRenato

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.

Overview

Progestin therapy with dienogest (D) or norethindrone acetate (N) is effective in reducing the size of ovarian endometriomas and related symptoms, but dienogest appears to be more effective in relieving symptoms and better tolerated.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To compare the effects of Dienogest (D) and Norethindrone acetate (N) in symptomatic women with ovarian endometriomas, analyzing the efficacy in reducing endometrioma size and symptom relief and drug tolerability. STUDY DESIGN: Retrospective study including 135 symptomatic women with ult...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejogrb.2019.04.010

データ提供：米国国立医学図書館（NLM）

Endometriosis: A Journey Towards Effective Management

Endometriosis, a challenging condition that affects many women, often requires careful navigation in the desert of treatment options. This study compares the effectiveness of two progestin therapies, dienogest (D) and norethindrone acetate (N), in managing ovarian endometriomas. The authors conducted a retrospective study to evaluate the efficacy of both treatments in reducing endometrioma size and alleviating symptoms. The study found that both D and N effectively reduced endometrioma size and symptoms, with D demonstrating greater symptom relief and better tolerability.

A New Path: Dienogest Emerges as a Promising Option for Endometriosis

This research highlights the potential of dienogest as a valuable treatment option for endometriosis. The study's findings suggest that dienogest offers greater symptom relief and better tolerability compared to norethindrone acetate, making it a potentially more effective and comfortable choice for many women.

A Brighter Horizon: Effective Management of Endometriosis

This study offers a beacon of hope for women struggling with endometriosis. The findings underscore the importance of exploring different treatment options and tailoring the approach to individual needs.

Dr. Camel's Conclusion

This research offers valuable insights into the effectiveness of dienogest and norethindrone acetate in managing ovarian endometriomas. The findings suggest that dienogest may be a more effective and well-tolerated option for many women. This study is a step towards a brighter future for women seeking effective management of endometriosis.

Date :
  1. Date Completed 2019-12-30
  2. Date Revised 2019-12-30
Further Info :

Pubmed ID

31132690

DOI: Digital Object Identifier

10.1016/j.ejogrb.2019.04.010

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・Side Effects of norethindrone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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