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Evaluation of brain SERT with 4-[<sup>18</sup>F]-ADAM/micro-PET and hearing protective effects of dextromethorphan in hearing loss rat model.

Author: ChenHsin-Chien, ChiuChuang-Hsin, HuangYuahn-Sieh, KangHsiao-Hsien, LiI-Hsun, LiuCheng-Tsung, MaKuo-Hsing, ShihJui-Hu, ShiueChyng-Yann, WangChih-Hung

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the protective effects of dextromethorphan (DXM) against noise-induced hearing loss (NIHL) in rats. DXM treatment improved hearing thresholds and prevented neurite degeneration of serotonergic neurons.
Paper Details　
Original Abstract of the Article :
This study investigated the protective effects of dextromethorphan (DXM) on noise-induced hearing loss (NIHL) in rats. This study aimed to improve the auditory threshold and to understand the protective effects of DXM against N-methyl-d-aspartate (NMDA)-induced neurite degeneration of serotonergic n...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/j.taap.2019.114604

データ提供：米国国立医学図書館（NLM）

Protecting Hearing: Dextromethorphan's Potential

Noise-induced hearing loss (NIHL) is a serious concern, like a desert wind that can erode our precious hearing. This study investigates the potential protective effects of dextromethorphan, a common cough suppressant, against NIHL. It's like discovering a hidden oasis in the desert of hearing loss, offering potential relief and protection.

Dextromethorphan: A Potential Shield Against Hearing Loss

The study found that dextromethorphan may offer protection against NIHL by reducing damage to the auditory system. This promising finding suggests that dextromethorphan could potentially play a role in preventing hearing loss, like a protective barrier against the harsh desert winds. However, further research is needed to confirm these findings and explore the potential applications of dextromethorphan in preventing NIHL.

Preserving Our Hearing in a Noisy World

This research highlights the importance of protecting our hearing from the damaging effects of noise. It's like carefully navigating a desert, taking precautions against the harsh elements. The study encourages further research into potential treatments and preventive measures, reminding us that the quest for preserving our hearing is an ongoing journey.

Dr.Camel's Conclusion

Noise-induced hearing loss, a silent threat in our noisy world, is like a desert wind that can slowly erode our ability to hear. This study provides a glimmer of hope, suggesting that dextromethorphan could potentially offer protection. We must continue to explore the desert of hearing research, seeking ways to preserve our hearing and protect ourselves from the damaging effects of noise.
Date :
  1. Date Completed 2020-05-20
  2. Date Revised 2020-08-25
Further Info :

Pubmed ID

31153898

DOI: Digital Object Identifier

10.1016/j.taap.2019.114604

Related Literature

Article Analysis
・Effects of dextromethorphan
SNS
PICO Info
in preparation
Languages

English

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