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High sustained virologic response rates of sofosbuvir-based regimens in Chinese patients with HCV genotype 3a infection in a real-world setting.

Author: DengHuan, FanXiude, HanQunying, LiNa, LiuZhengwen, WangXiaoyun, WangYe, ZhangKun, ZhangXiaoge

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Sofosbuvir/velpatasvir and sofosbuvir/daclatasvir are highly effective and well-tolerated in patients with hepatitis C virus (HCV) genotype 3a infection, regardless of cirrhosis status. The addition of ribavirin or extending the treatment duration did not significantly improve the sustained virologic response (SVR) rates.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Patients with hepatitis C virus (HCV) genotype 3 infection remain a difficult-to-cure population. This study evaluated the efficacy and safety of sofosbuvir-based regimen in genotype 3 patients in a real-world setting. METHODS: HCV genotype 3a-infected adults with compensated liver dise...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547524/

データ提供：米国国立医学図書館（NLM）

Sofosbuvir-Based Regimens: A Powerful Weapon Against Hepatitis C

This research delves into the field of hepatology, focusing on the treatment of Hepatitis C, a viral infection that affects the liver. The study evaluates the efficacy and safety of sofosbuvir-based regimens in patients infected with Hepatitis C genotype 3a, a particularly challenging subtype.

Sofosbuvir's Success in Eradicating Hepatitis C

The study found that sofosbuvir-based regimens, specifically those involving sofosbuvir/velpatasvir and sofosbuvir/daclatasvir, achieved remarkably high sustained virologic response rates in patients with Hepatitis C genotype 3a infection. The study also discovered that the addition of ribavirin and the duration of treatment did not significantly improve the response rate.

Hope for Hepatitis C Patients: Effective Treatment Options

This research provides encouraging news for individuals battling Hepatitis C. The high efficacy of sofosbuvir-based regimens offers a powerful tool for eliminating the virus and preventing long-term liver damage.

Dr.Camel's Conclusion

This study presents a hopeful vision for Hepatitis C treatment, like a desert oasis offering relief from the harsh realities of the disease. Sofosbuvir-based regimens provide a beacon of hope for patients seeking a cure.

Date :
  1. Date Completed 2019-08-15
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

31159813

DOI: Digital Object Identifier

PMC6547524

Related Literature

Article Analysis
・Side Effects of daclatasvir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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